Hematology Flashcards
What is the normal range for MCV
80 to 100
What is the most common microcytic anemia
Iron deficiency anemia
Would anemia of chronic disease most likely be macrocytic, normocytic or microcytic
Normocytic
What two main causes should you be thinking of in a macrocytic anemia
Malnutrition and severe blood loss
Does an increase in reticulocytes indicate a decrease or increase in red blood cell production
An increase, reticulocytes are newly released baby RBCs
Auer Rods are most commonly associated with what disease
Acute myeloid leukemia
What molecule binds iron in the blood stream
Transferrin
What does koilonychia refer to
Spoon shape nails which may be found in microcytic anemia
Well the serum ferritin be high or low in a patient with iron deficiency anemia
It will almost always be low
A low retic count in a normal serum ferritin should make you think of what diagnosis
Anemia of chronic disease
Under normal conditions at what hemoglobin level would you begin to consider a transfusion
8
Asplenim secondary to sickle cell disease increases a patient risk for what type of infections
Capsulated organisms like strep pneumonia and H flu
An African American teenager present with a vascular necrosis of his right femoral head what is the most likely diagnosis
Sickle cell disease
How do you treat a sickle cell crisis
Fluids, oxygen, pain medication, transfusion maybe necessary
Will unconjugated Bilirubin be high or low in a patient with sickle cell disease
High
Which anemia should you think of if you see the term Howell-jolly bodies
Sickle cell due to the functional asplenia, but it may also show up and a folic acid deficiency
G6PD deficiency followed what pattern of inheritance
X linked
List the three diagnosis you should be thinking of if it question includes Heinz bodies
G6PD deficiency anemia
Chronic liver disease
Alpha thalassemia
What is pica
Eating nonfood items including ice, paper, dirt, hair
Are target cells seen in mild or severe iron deficiency anemia
Severe, they are also seen in alpha thalassemia, chronic liver disease, and asplenia
Iron deficiency anemia will have a serum iron lower than what value
30
Would a B 12 deficiency anemia most likely be microcytic, normocytic or macrocytic
Macrocytic
You should be thinking alpha thalassemia if the question stem includes which four geographic areas
South east Asia, China, Middle East, Africa
A patient of Mediterranean descent is a clue for which type of anemia
Beta thalassemia
In a folic acid deficiency anemia the folic acid level is typically below what
<150
What hematological disorders should you think of if the question talks about the patient eating ice or dirt
Iron deficiency anemia
Inability to absorb vitamin B 12 due to lack of intrinsic factor is what disease
Pernicious anemia
Stocking glove paresthesias should make you think of what two diagnosis
B12 deficiency neuropathy in diabetic neuropathy
Will the RBCs be large, small, or normal size in a B12 deficient anemia
Macrocytes
Will the retic count be elevated decreased or normal in a B 12 deficiency anemia
Retic count will be low. Low building blocks means low production
What is Shilling‘s test used for
Test for the cause of a B 12 deficiency
Strict vegans are at risk for what type of anemia
B 12 deficiency anemia
Is sickle cell microcytic, macrocytic or normocytic
Normocytic
Will hemolytic anemia generally have an elevated or decreased retic count
Elevated
List for disease states in which you may find basophilic stippling
Lead poisoning, beta or Alpha thalassemia, sideroblastic anemia, arsenic poisoning
If a question presents a pregnant woman with anemia what is the most likely diagnosis
Iron deficiency anemia
The term Philadelphia chromosome should make you think of what diagnosis
Chronic myeloid leukemia
