Hematology

Question 1

What is the normal range for MCV

Answer 1

80 to 100

Question 2

What is the most common microcytic anemia

Answer 2

Iron deficiency anemia

Question 3

Would anemia of chronic disease most likely be macrocytic, normocytic or microcytic

Answer 3

Normocytic

Question 4

What two main causes should you be thinking of in a macrocytic anemia

Answer 4

Malnutrition and severe blood loss

Question 5

Does an increase in reticulocytes indicate a decrease or increase in red blood cell production

Answer 5

An increase, reticulocytes are newly released baby RBCs

Question 6

Auer Rods are most commonly associated with what disease

Answer 6

Acute myeloid leukemia

Question 7

What molecule binds iron in the blood stream

Answer 7

Transferrin

Question 8

What does koilonychia refer to

Answer 8

Spoon shape nails which may be found in microcytic anemia

Question 9

Well the serum ferritin be high or low in a patient with iron deficiency anemia

Answer 9

It will almost always be low

Question 10

A low retic count in a normal serum ferritin should make you think of what diagnosis

Answer 10

Anemia of chronic disease

Question 11

Under normal conditions at what hemoglobin level would you begin to consider a transfusion

Answer 11

8

Question 12

Asplenim secondary to sickle cell disease increases a patient risk for what type of infections

Answer 12

Capsulated organisms like strep pneumonia and H flu

Question 13

An African American teenager present with a vascular necrosis of his right femoral head what is the most likely diagnosis

Answer 13

Sickle cell disease

Question 14

How do you treat a sickle cell crisis

Answer 14

Fluids, oxygen, pain medication, transfusion maybe necessary

Question 15

Will unconjugated Bilirubin be high or low in a patient with sickle cell disease

Answer 15

High

Question 16

Which anemia should you think of if you see the term Howell-jolly bodies

Answer 16

Sickle cell due to the functional asplenia, but it may also show up and a folic acid deficiency

Question 17

G6PD deficiency followed what pattern of inheritance

Answer 17

X linked

Question 18

List the three diagnosis you should be thinking of if it question includes Heinz bodies

Answer 18

G6PD deficiency anemia
Chronic liver disease
Alpha thalassemia

Question 19

What is pica

Answer 19

Eating nonfood items including ice, paper, dirt, hair

Question 20

Are target cells seen in mild or severe iron deficiency anemia

Answer 20

Severe, they are also seen in alpha thalassemia, chronic liver disease, and asplenia

Question 21

Iron deficiency anemia will have a serum iron lower than what value

Answer 21

30

Question 22

Would a B 12 deficiency anemia most likely be microcytic, normocytic or macrocytic

Answer 22

Macrocytic

Question 23

You should be thinking alpha thalassemia if the question stem includes which four geographic areas

Answer 23

South east Asia, China, Middle East, Africa

Question 24

A patient of Mediterranean descent is a clue for which type of anemia

Answer 24

Beta thalassemia

Question 25

In a folic acid deficiency anemia the folic acid level is typically below what

Answer 25

<150

Question 26

What hematological disorders should you think of if the question talks about the patient eating ice or dirt

Answer 26

Iron deficiency anemia

Question 27

Inability to absorb vitamin B 12 due to lack of intrinsic factor is what disease

Answer 27

Pernicious anemia

Question 28

Stocking glove paresthesias should make you think of what two diagnosis

Answer 28

B12 deficiency neuropathy in diabetic neuropathy

Question 29

Will the RBCs be large, small, or normal size in a B12 deficient anemia

Answer 29

Macrocytes

Question 30

Will the retic count be elevated decreased or normal in a B 12 deficiency anemia

Answer 30

Retic count will be low. Low building blocks means low production

Question 31

What is Shilling‘s test used for

Answer 31

Test for the cause of a B 12 deficiency

Question 32

Strict vegans are at risk for what type of anemia

Answer 32

B 12 deficiency anemia

Question 33

Is sickle cell microcytic, macrocytic or normocytic

Answer 33

Normocytic

Question 34

Will hemolytic anemia generally have an elevated or decreased retic count

Answer 34

Elevated

Question 35

List for disease states in which you may find basophilic stippling

Answer 35

Lead poisoning, beta or Alpha thalassemia, sideroblastic anemia, arsenic poisoning

Question 36

If a question presents a pregnant woman with anemia what is the most likely diagnosis

Answer 36

Iron deficiency anemia

Question 37

The term Philadelphia chromosome should make you think of what diagnosis

Answer 37

Chronic myeloid leukemia