Hematology Flashcards

1
Q

Connective tissue composed of cells suspended within a liquid intercellular matrix

A

Blood

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2
Q

Liquid Intracellular matrix withing which blood is suspended

A

Plasma

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3
Q

Blood color for oxygenated _____ , and low oxygen _____

A

Bright red, dark blueish red

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4
Q

Quantity of blood in an average person

A

5 liters

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5
Q

Viscosity of Blood

A

3 to 4 times thicker than water

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6
Q

Blood composition, percentage ____% plasma, and
____% formed elements

A

52-58%, 42 -48%

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7
Q

Measurement of the percent formed elements in the blood

A
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8
Q

Formed elements components, ____, _____, and _____

A

Red blood cells (Corpuscles), White blood cells (Leukotocytes) and, Platelets (Thrombocytes)

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9
Q

Red Corpuscles

A

Red blood cells

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10
Q

Leukotocytes

A

White Blood cells

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11
Q

Thrombocytes

A

Platelets

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12
Q

Blood pH

A

slightly alkaline around [ 7.4 ]

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13
Q

Vital molecule found in erythrocytes, consisting of globular protein portion (globin) and four heme groups

A

hemoglobin

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14
Q

Oxygenated Hemoglobin

A

Oxyhemoglobin

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15
Q

Hemoglobin w/o oxygen

A

Reduced Hemoglobin

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16
Q

Hemoglobin with carbon dioxide bound to it

A

Carbaminohemoglobin

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17
Q

In red marrow, this is the precursor cell for all blood cells

A

hemocytoblast

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18
Q

In red blood cells the HEMOCYTOBLAST develops into this rapidly dividing cell

A

erythroblast

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19
Q

Red cells released from the bone marrow

A

reticulocytes

(the presence of these in the blood indicates active bone marrow)

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20
Q

There are _____ million erythrocytes per cubic mm. of blood

A

4.5 to 5.5

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21
Q

of the 75 trillion cells in the human body 25 trillion are _____

A

erythrocytes

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22
Q

Two vitamins required for DNA synthesis in diving cells are _____ and _____

A

Vitamin B and Folic Acid

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23
Q

Type of factor the stomach lining contains, that promotes the absorption of vitamin B12

A

Intrinsic

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24
Q

This hormone, that is produced by the liver and kidneys, stimulates erythrocyte production

A

erythropoietin

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25
Q

A type of Erythrocyte abnormality, a REDUCED HEMATOCRIT with a decrease in red cell count

A

Anemia

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26
Q

Inadequate dietary Iron intake causes this

A

Iron deficiency anemia

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27
Q

This is caused by red marrow failure as can occur in radiation exposure

A

Aplastic anemia

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28
Q

This is caused by substitution of improper amino acids in the hemoglobin molecules

A

Sickle Cell Anemia

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29
Q

This is an increase in Hematocrit with the concentration of red blood cells above normal

A

Polycythemia

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30
Q

Three types of Granular Leukocytes, ______,
______, and _______

A

Neutrophils, Eosinophils, Basophils

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31
Q

These Granular Leukocytes make up 60% of the total number of white cells, they are micro-phagocytes

A

Neutrophils

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32
Q

These Granular Leukocytes compose less than 3% of the total number of white cells, ACIDIC STAINS, and involved with detoxification of foreign proteins entering the lungs and digestive system

A

Eosinophils

33
Q

These Granular Leukocytes make up less than 1% of white cells, act by releasing heparin and histamine at the site of damaged tissue

A

Basophils

34
Q

This is a vasoactive agent that increases blood flow to the affected area, and allows the space to fill with fluid

A

Histamine

35
Q

This prevents the formation of blood clots helping them to maintain continuous blood flow to damaged tissue

A

Heparin

36
Q

Two types of Agranular Leukocytes _____, and _____

A

Lymphocytes, and Monocytes

37
Q

This type of agranular leukocyte composes about 30% of white cells, are the key players in specific immunological defense (immune) system

A

Lymphocytes

38
Q

This type of agranular leukocytes are the largest of the white cells, making up about 5% of the white cell count, act as macrophagocytes digesting large amounts of debris with lysosomal enzymes

A

Monocytes

39
Q

There are usually ____to _____ thousand leukocytes per cubic mm of blood

A

5-10

40
Q

Neutrophils, Eosinophils, Basophils, and monocytes are examples of this _______ response

A

inflammatory

41
Q

Decrease in the number of circulating white cells

A

Leucopenia

42
Q

Increase in the white blood cell count

A

Leukocytosis

43
Q

Cancer of the leukocytes

A

Leukemia

44
Q

Cancer of the leukocytes, which were derived from the bone marrow

A

Myeloid Lukemia

45
Q

Cancer of the leukocytes, which are associated with the lymph nodes

A

Lymphoid Leukemia

46
Q

with leukemia the patients resistance to infection is _____ due to the cells being both anatomically and functionally abnormal

A

Decreased

47
Q

This refers to the prevention of blood loss

A

Hemostasis

48
Q

Platelets, important for plugging the hundreds of small ruptures that occur throughout the vasculature each day

A

Thrombocytes

49
Q

Thrombocytes are fragments of these LARGE cells that like other blood cells are derived from hemocytoblasts in red bone marrow

A

Megakaryocytes

50
Q

There are around ____ to _____ thousand platelets per cubic mm. of blood

A

150 to 350

51
Q

At the site of a rupture platelets will act as plugs and release this vasoconstrictor that reduces blood flow in a damaged vessel

A

Serotonin

52
Q

The synthesis of prothrombin in the liver requires this vitamin

A

Vitamin K

53
Q

This factor produced by the liver, circulates in inactive form in the plasma

A

Fibrinogen

54
Q

Damaged vessels release this kind of substance that causes prothrombin to be converted to thrombin (active form)

A

Activator

55
Q

This active form of prothrombin

A

Thrombin

56
Q

These ions are necessary for the activation of prothrombin to thrombin

A

Calcium

57
Q

The activation of prothrombin leads to the conversion of fibrinogen to this,

A

Fibrin

58
Q

these proteins form long strands that intertwine making a meshwork over a ruptured area, ultimately pulling the ends of the rupture together

A

Fibrin

59
Q

This is a type of clotting abnormality, is a genetic disease characterized by lack of one of the clotting factors

they don’t bleed more, but they bleed longer which lead to more blood loss

A

hemophilia

60
Q

A stationary clot that actually plugs the vessel itself is called this

A

Thrombus

61
Q

A wandering clot, one that has become dislodged from the vessel wall is called this

A

Embolus

62
Q

Plasma is made up of 92% what

A

water

63
Q

Water, salts, hormones, gases, nutrients, waste products and liver proteins make up

A

Plasma

64
Q

The three types of liver proteins that make up part of plasma are _____, ______, and _______

A

Albumin, Globulins, and Clotting factors

65
Q

This liver protein aids in maintaining colloidal osmotic pressure, also acts as a CARRIER for certain other blood borne groups

A

Albumin

66
Q

This liver protein transports certain fat molecules and vitamins in the blood,

A

Globulins

67
Q

A class of globulins that is produced by lymphocytes and act as antibodies

A

Gamma Globulins

68
Q

This kind of liver protein, including prothrombin and fibrinogen, prevents blood loss and aids in hemostasis

A

Clotting Factors

69
Q

The most familiar blood group

A

ABO group

70
Q

Universal donor blood group

A

Type O

71
Q

Universal recipient blood group

A

Type AB

72
Q

Blood group first discovered in rhesus monkeys

A

Rh group

73
Q

what percent of the human population is Rh +

A

85%

74
Q

The first line of defense against harmful pathogens

A

external barriers of the body, skin, mucous membranes

75
Q

The second line of defense against harmful pathogens

A

internal physiological mechanisms, phagocytosis, inflammation and fever

76
Q

The third line of defense against harmful pathogens is

A

The immune system (Recognize, react, remember)

77
Q

The part of the antigen that serves as the recognition factor

A

epitope

78
Q

This is released by a T helper cell, and stimulates the programmed B cell to divide repeatedly forming clones

A

Interleukin