Hematologic Disorders

Question 1

7 causes of Iron Deficiency Anemia

Answer 1

Prenagnancy
Diet
Bleeding (Menstruation)
Alcoholism
Malabsorption
MCV
Transferrin

Question 2

How malabsorption of iron happens?

Answer 2

Gastritis cause low HCl

Chronic: Low iron absorption in the duodenum

Question 3

Size of RBC in the Mean Corpuscular Volume

Answer 3

Microcytic Anemia

Question 4

Iron bound anemia which high _______ signifies low iron

Answer 4

Transferrin

Question 5

7 Clinical Manifestations of Iron Deficiency Anemia

Answer 5

Appearance: Pallor not Pale
Dyspnea
Weakness and Fatigue
Inflamed mucus membrane NOT PALE

Cheilosis
Koilonychia
Pica

Question 6

Auto immune disorder caused by Hypoplastic bone marrow

Answer 6

Aplastic anemia

Question 7

All absent pancytopenia

Answer 7

Aplastic anemia

Question 8

Prioritizatiion for Aplastic Anemia

Answer 8

1. Bleeding: Low platelet
2. Infection: Low wbc
3. Anemia: Low RBC

Question 9

MGT for Aplastic Anemia

Answer 9

Bone Marrow Transplant
Cyclosporine
Blood transfusion
Precautions

Question 10

Cyclosporine WOF?

Answer 10

Immunosuppresant

Question 11

Hgb 7

Answer 11

patient will go to heaven

Question 12

Mgt for Aplastic anemia
(Non pharma)

Answer 12

Rest and o2

Question 13

Watch out for! Aplastic Anemia

Answer 13

Bleeding: mouth, nose, Anus
Soft diet only
Avoid injections
Avoid Anal thermometer
High fiber
Soft toothbrush, no dental floss
Electric razor
No aspirin
Contact sports

Question 14

WOF for infections for Aplastic Anemia

Answer 14

Common sites: Skin, Respi, Gastro
Reverse Isolation
Crowded places
Avoid ill person
Fresh raw fruits (-)
No to dirty activity

Question 15

caused by B12 folic acid deficiency

Answer 15

Megalobastic anemia

Question 16

MCV size of a patient with Megaloblastic Anemia

Answer 16

Macrocyctic??

Large and Immature

Question 17

What phase in cell cycle needs B12

Answer 17

S-phase

Question 18

G2 cell growth purpose

Answer 18

Synthesis of DNA and Myelin

Question 19

4 Causes of Megaloblastic Anemia

Answer 19

Malnutrition
Alcoholism
Pregnancy
Gastrectomy and Resection of Ileum

Question 20

Only anemia with neuro signs

Answer 20

Pernicious Anemia

Question 21

Also caused by B12 deficiency, Low intrinsic factor and Myelin

Answer 21

Pernicious Anemia

Question 22

Neuro signs of Pernicious Anemia

Answer 22

Paresthesia
Numbness
Loss of balance

Question 23

MGT for Pernicious Anemia

Answer 23

IM and Oral B12

Question 24

Checks presence or absence of intrinsic factor

Answer 24

Schilling Test

Question 25

normal schilling test

Answer 25

High B12 in urine more than 10%

Question 26

Presence of Hgb5
Low glutamic acid causes Valine

Answer 26

Sickle Cell Anemia

Question 27

Sickle cell crisis of newborn arises at

Answer 27

5-6 months

Question 28

Triggering factors of SCA

Answer 28

Cold temp
Dehydration
Stress
High altitude
Infectiion

Question 29

Infection for SCA

Answer 29

Human Parvovirus

Question 30

a rare disorder in which the blood doesn’t clot in the typical way because it doesn’t have enough blood-clotting proteins (clotting factors

Answer 30

Hemophilia

Question 31

most common type of hemophilia.
X linked recessive
Man - Manifests
Women - Carrier

Answer 31

Hemophilia A - Factor 8

Question 32

Xmas Diseases
Factor 9 gene

Answer 32

Hemophilia B

Question 33

also known as factor 11 (factor XI) deficiency. This hemophilia type is very rare

Answer 33

Hemophilia C

Question 34

Interventions for hemophilia

Answer 34

FFP: Cryoprecipitate
WOF: FVE

Question 35

Interventions for Hemophilai

Answer 35

Monitor S/Sx of Bleeding
Education about pain management and Promote joint protection