Hematologic disorders Flashcards
WBC low values potential cause
Bone marrow suppression
Autoimmune disorders
Immunosuppressive disorders
Overwhelming infection
Caner that spreads to bone marrow
WBC high values potential cause
Dehydration
infection
inflammatory conditions
some malignancies
may be elevated in late preg and during labor
Traumatic injury
Neutrophils high values causes
-Acute bacterial infection
-Inflammation or tissue necrosis
-Some malignancies
-Cushing syndrome
-Increased immature forms (band and stabs) sometime called shift to left with ongoing acute bacterial infection
Neutrophils low value cause
Bone marrow suppression
Autoimmune disorders
Immunosuppressive disorders
Overwhelming infection
Cancer that spreads to bone
Basophils low value cause
occasional low number is usually not medically significantf
Basophils high value cause
Hypersensitivity reaction
Chronic inflammatory disorders
Some leukemias
Uremia
Eosinophils low value cause
Occasional low number is usually not medically significant
Eosinophils high value cause
Allergic reaction
Parasitic infections
Chronic inflammatory disorders
some malignancies
Addison disease
Lymphocytes low value cause
Autoimmune disorders
Debilitating illness
Immunodeficiency syndromes
Some malignancies
Corticosteroids
Lymphocytes high value cause
Acute viral infection
Chronic bacterial infection
Chronic inflammatory disorders
Some malignancies
Monocytes low value cause
Chronic disease….rare
Monocytes high value cause
Chronic infection
Recovery phase of infections
Some malignancies
MCV
Microcytic (<80 fl)
Normocytic (80-100 fl)
Macrocytic (>100 fl)
Causes of microcytic anemia
iron deficiency anemia
Thalassemia trait
Causes of Normocytic anemia
Anemia of chronic disease
hemolysis
sickle cell disease
renal failure
