Hematologic And Renal Emergencies Flashcards
Solid components of blood are created in
The bone marrow that forms specialized core of many of the body’s bones.
RBC’s
Majority of cells in circulation, give blood red color, have specialized molecules called Hemoglobin that bind to oxygen and deliver oxygen to cells
WBC’s
Critically respond to infection and are major mediators of the body’s immune response
Platelets
Crucial in formation of clots
Clumping (aggregation) most rapid response to stop bleeding at injured site
What prevents aggregation of platelets
Aspirin, given to acute heart attack patient or potential heart attack
Situation of unwanted clumping of platelets not desirable?
When plaque in a coronary artery ruptures because it can cause a clot that then completely blocks the coronary artery leading to heart attack ( myocardial infarction )
Plasma
Liquid that blood and platelets are suspended, contains dissolved nutrients and crucial proteins like clotting factors
Two components in blood responsible for clotting
Platelets and clotting factors
describe Clotting cascades
Coagulopathy
Abnormal clotting of blood
When can Coagulopathy occur
When the body forms clots too readily or when the patient clots too slow = uncontrolled bleeding
Too slow coagulopathies
Are due to abnormally slow clotting by problems with clotting cascade a result of too few platelets or platelets that are not functioning correctly.
Diseases prone to poor clotting
Advance Liver Disease (clotting fractures made in liver)
Ex) Cirrhosis - not make adequate clotting factors
Genetic
Ex) Hemophiliacs - Von willebrand Disease most common inherited
Platelets functional defective allowing excessive bleeding
Medical conditions that worsen disease
Risk heart attack or strokes or abnormal cardiac rhythm like atrial fibrillation
Giving blood thinners
Blood thinners med
Coumadin , pradaxa, eliquis, xarelto, Lovenox
Inhibit certain clotting factors
Manage patients with potential coagulopathies past medical history
History of Dysrhymia called atrial fibrillation are common blood thinners
Ask trauma patients if taking blood thinners