HEMA1 Flashcards
Anemia can be caused by:
BOTH
A classification of anemia wherein the MCV is
greater than 96ft. MCHC is normal
MACROCYTIC NORMOCHROMIC ANEMIA
Impaired release of storage iron associated with increased HEPCIDIN levels is due to:
IRON DEFICEINCY
Caused by blocks on the protoporphyrin pathway resulting in defective hemoglobin synthesis and iron overload:
SIDEROBLASTIC ANEMIA
An anemia with normocytic/normochromic
anemia with characteristic course basophilic
slipping:
LEAD POISONING
A falsely elevated HCT is obtained. Which of the
following calculated values will not be affected?
MCH
Which of these types of anemia are under the
category of impaired production?
ALL OF
THESE
SITUATION: RBC indices obtained on a patient
are as follows: MCV 88um3 fL; MCH 30pg; MCHC 34% (340). The RBCs on the peripheral smear would appear.
NORMOCYTIC, NORMOCHROMIC
In an uncomplicated case of severe iron
deficiency anemia, which of the following sets
represents the typical pattern of results?
C
What is the first type of cell produced by the
developing embryo?
ERYTHROCYTE
As most blood cell lines mature, which of the
following is characteristics?
NUCLEUS TO CYTOPLASM RATION (N:C) DECREASES
The direct antiglobulin test is often positive in:
ACQUIRED HEMOLYTIC ANEMIA
The anemia of chronic infection is characterized by:
DECREASED SERUM IRON LEVELS
A patient is admitted with a history of chronic
bleeding secondary to peptic ulcer. Hematology
workup reveals a sever microcytic, hypochromic
anemia. Iron studies were requested. Which of
the following would be expected in this case?
RESULT C
Which of the following sets of laboratory findings is consistent with hemolytic anemia?
DECREASE ERYTHROCYTE SURVIVAL;
INCREASED CATABOLISM OF HEME
Chronic blood loss can lead to:
IRON
DIFICIENCY
Many micro-spherocytes, schistocytes and
budding off of spherocytes can be seen on
peripheral blood smear of patients with:
EXTENSIVE BURNS
Abetalipoproteinemia is characterized by mild
anemia and numerous____ on the peripheral
blood smear
ACANTHOCYTES
What is the most common cause of iron
deficiency?
BLEEDING
Ineffective erythropoiesis is/are due to the
following, EXCEPT:
IRON DEFICIENCY
This red cell parameter is increased in iron
deficiency anemia:
TIBC
When there is defective G6PD in red cells, then
the cause of hemolysis is:
INTRINSIC
In chronic post-hemorrhagic anemia, this is NOT TRUE.
RETICULOCYTE COUNT IS VERY
LOW
Isoimmune hemolytic disease of the newborn
maybe due to:
ABO INCOMPATIBILITY
In aplastic anemias, marrow cellularity is:
DECREASED
Rh null disease person shows morphological
changes in red cells. Persons with Rh-negative
condition possesses the CDE antigen:
1ST STATEMENT IS TRUE; 2ND STATEMENT IS NOT TRUE
Acanthocytes and echinocytes can be
differentiated based on which of the following:
ALL OF THESE
The opposite of aplastic anemia is:
POLYCYTHEMIA
Extrinsic Hemolytic Anemia is caused by:
ALL OF THESE
Defect of red cell itself usually hereditary &
grouped as membrane, metabolic or hemoglobin defects:
INTRINSIC HEMOLYTIC ANEMIA
Anemia most commonly present with which one of the following set of symptoms:
SHORTNESS OF BREATH AND FATIGUE
Which one of the following conditions would be
included in the differential diagnosis of an
anemic adult patient with an MCV of 125fL and
an RDW of 20% (reference interval: 11.5% to
14.5%)
VITAMIN 12 DEFICIENCY
Schistocytes, ovalocytes, and acanthocytes are
examples of abnormal changes in RBC:
SHAPE
Which of the following is detectable only by
examination of a peripheral blood film? .
POIKILOCYTOSIS
Which of the following patients would be
considered anemic with a hemoglobin value of
14.5g/dL?
A NEWBORN BOY
What are the initial laboratory tests that are
performed for the diagnosis of anemia?
CBC, RETICULOCYTE COUNT, AND PERIPHERAL
BLOOD FILM EXAMINATION
An increased in which one of the following
suggests a shorted life span of RBCs and
hemolytic anemia?
RETICULOCYTE COUNT
An autoimmune reaction destroys the
hematopoietic stem cells in the bone marrow of a young adult patient, and the amount of active
bone marrow, including erythroid precursors, is
diminished. Erythroid precursor that are present are normal in appearance, but there are too few to meet the demand for circulating red blood cells, and anemia develops. The reticulocyte count is low. The mechanism of the anemia would be described as:
INSUFFICIENT
ERYTHROPOIESIS
Which of the following are important to consider in the patient’s history when investigating the cause of an anemia?
ALL OF THESE
To determine which of the following condition
would be included in the differential diagnosis of an anemic adult patient with an absolute
reticulocyte count of 20 3 109 /L and an MVC of
65fL
IRON DEFICIENCY