CC1 Flashcards
Milky appearance of serum specimen causes falsely elevated bilirubin. Bilirubin is also increased if sample is hemolyzed.
A. ONLY 1ST STATEMENT IS TRUE
Which of the following does not affect ammonia
levels?
I. Hemolysis
II. Incorrect Blood-to-additive ratio
III. Tobacco exposure
IV. Cold transport
V. Prolonged tourniquet Application
VI. Fasting
IV, VI
All of these amino acids have maximum absorbance at 210nm, except:
TRYPTOPHAN
Which of the following coagulation factors is not dependent to Vitamin K?
LABILE FACTOR
Source of bilirubin
ALL OF THESE
Principle of Biuret Method is based on____.
E
Slow-reacting Bilirubin is produced from reduction of biliverdin. What enzyme reduces biliverdin?
BILIVERDIN REDUCTASE
Rotor Syndrome: Bilirubin Excretion Deficit: ____: Circulating conjugation inhibitor
LUCEY-DRISCOLL SYNDROME
In bilirubin transport deficit, non-polar bilirubin is _____ while total bilirubin is _____.
INCREASED INCREASED
Which of the following is/are hepatic enzymes?
I. Aldolase
II. Lactate Dehydrogenase
III. Acid Phosphatase
IV. Gamma-Glutaryl Transferase
II, IV
Enzyme employed in ammonia measurement
utilizing automated analyzers
E
In hemolytic anemia, hemobilirubin is ____while
urobilinogen is ____
INCREASED, NORMAL
Albumin is the most abundant protein in the blood. In serum protein electrophoresis, it migrates nearest to the point of origin.
ONLY 1ST STATEMENT IS TRUE
In post-hepatic jaundice, polar bilirubin is____ while non-polar bilirubin is ____.
INCREASE, NORMAL
Cigler-Najjar syndrome is a type of unconjugated hyperbilirubinemia due to:
ABSENCE OF CONJUGATING ENZYME
Purpose of methanol in Evelyn and Molly
BOTH
Diazo A: 0.1% Sulfanilic acid with HCl; Diazo B: ____.
0.5% SODIUM NITRITE
Ammonia is a neurotoxin leading to coma. Urea is synthesized from ammonia through the Krebs cycle.
ONLY 1ST STATEMENT IS TRUE
MacDonald Method: Test for _____; Albumin
Measurement: Test for liver Synthetic Function
LIVER EXCRETORY FUNCTION
1 marker for obstructive jaundice
ALKALINE PHOSPHATASE
Kjedahl method assumes that the nitrogen content of protein is approximately ____
16%
Veronal in SPE___ pH of the medium which causes protein to be ____
INCREASES, NEGATIVELY CHARGED
In serum protein electrophoresis, protein migrates towards the _____
POSITIVELY-CHARGE ELECTRODE
Urobilinogen is produced by reduction of non-polar bilirubin by intestinal bacteria. Measurement of bilirubin utilizes p-phenylenediamine dihydrochloride.
BOTH STATEMENT ARE FALSE
All proteins are synthesized by the liver except for immunoglobulins, Antibodies migrate nearest to the point of origin during serum protein electrophoresis
BOTH STATEMENT ARE TRUE
Plasma is not utilized in total protein measurement as:
BOTH ARE CORRECT
Kernicterus may occur on patients with chronic
elevation of which bilirubin?
ALL OF THESE
Abnormal bilirubin increased in Dubin Johnson
Syndrome
BOTH B AND C
Which of this dye will only bind to albumin?
BROMCRESOL PURPLE
Pre-hepatic bilirubin is carried by albumin to the liver. In the liver, this bilirubin is carried by
ligandins
BOTH STATEMENT ARE TRUE
Storage temperature of specimen for Urea
measurement.
2-8C
To convert BUN to Urea, the value is multiplied to:
2.14
Lloyd’s Reagent: ___ Fuller’s Earth Reagent:
Aluminum Magnesium Silicate
SODIUM ALUMINUM SILICATE
Type of azotemia associated with decreased blood delivered to the kidneys.
PRE-RENAL
AZOTEMIA
Normal Creatinine-to-BUN ration
1:20
Uric acid occurs as monosodium urate in plasma at a blood pH of:
ALL OF THESE
____: Jaffe reagent; Bilirubin: Diazo reagent
CREATININE
Arrange the following NPNs in ascending order of abundance
VI-II-I-V-IV-III
Major site of reabsorption of essential substances in the nephrons
PROXIMAL CONVOLUTED
TUBULES
Uricase enzyme causes oxidation of Uric Acid
forming:
ALLANTOIN
