CC2 Flashcards
Elevation of serum alkaline phosphatase may be seen in:
1. Hepatobiliary disease
2. Growing children
3. Hyperparathyroidism
4. Germ cell tumor of the testicle
1 AND 2
The following statements are TRUE of lactate
Dehydrogenase
1. There is an elevated serum LD in Acute
Myocardial Infraction
2. There is a decreased LD in Megaloblastic
Anemia
3. There are 4 monomers in the LD isoenzyme
structure
4. LD6 isoenzyme is seen only in patient with
muscle disorders
1 and 3
Amylase is an enzyme useful in diagnosis of Acute
pancreatitis. Which of the following statements
correctly describes amylase?
1. Amylase is elevated in acute pancreatitis,
mumps, parotitis, and perforated peptic ulcer
2. Amylase cleaves glycosidic bons of
polysaccharides
3. It is the largest of all enzyme in terns of
molecular weight
4. The p-type isoenzyme migrates fastest while
the S-type isoenzyme migrates slowest in
amylase isoenzyme electrophoresis
1 and 2
Which of the following statements is TRUE of
isoenzyme LD-2?
IT IS PRESENT IN GREATEST
AMOUNT IN NORMAL HEART TISSUE
Which of the following enzyme is considered a
newborn screening marker?
G-6-PD
A scanning of CK isoenzyme fractionation two
peaks: a slow cathodic peak (CK-MM) an
intermediate peak (CK-MB). A possible
interpretation for this pattern is:
MYOCARDIAL
INFRACTION
The clinical significance of an elevated acid
phosphatase is:
PROSTATIC DISEASE
Tests for acid phosphatase detect levels of the
enzyme from tissues such as:
LIVER
SPLEEN,
POSTATE
PLATELETS
Select the product formed from the forward
reaction of AST:
OXALOACETATE AND
GLUTAMATE
Creatine kinase is frequently elevated in disorders such as acute myocardial infraction and:
DUCHENNE MUSCULAR DYSTROPHY
This enzyme is the most specific marker of acute pancreatitis and remains elevated for 48hrs in the blood circulation:
LIPASE
This enzyme which affects the cell membrane and microsomal fractions, is a sensitive indicator of occult alcoholism?
GGT
Which two condition can “physiologically” elevate serum alkaline phosphatase?
GROWTH, 3RD TRIMESTER OF PREGNANCY
A physician suspects his patient has pancreatitis. Which test(s) would be most indicative of this disease?
AMYLASE
Which of the following chemical determinations
may be of help in establishing the presence of
seminal fluid?
ACID PHOSPHATASE
Increased total serum Lactate Dehydrogenase (LD) activity, confined to fractions 4 and 5, is most likely to be associated with:
ACUTE VIRAL
HEPATITIS
Regan isoenzyme has the same properties as
alkaline phosphatase that originates in the:
PLACENTA
The most sensitive enzymatic indicator for liver
damage from ethanol intake is
GGT
A serum sample drawn in the emergency room
from a 42-year-old man yielded the following
laboratory results:
CK: 185 units (Normal = 15-160)
AST: 123 units (Normal = 0-48)
CK-MB: 6 units (Normal = 2012)
Which of the following conditions might account for these values?
CRUSH INJURY TO THE THIGH
Which of the following enzymes catalyzes the
conversion of starch to glucose and maltose?
AMYLASE
Which of the following is a glycolytic enzyme that catalyze the cleavage of fructose-1.6-diphosphate to glyceraldehyde -3-phosphate and dihydroxyacetone phosphate?
PHOSPHOFRUCTOKINASE
Which of the following sets of results would be
consistent with macroamylasemia?
INCREASED SERUM AMYLASE AND NORMAL
URINE AMYLASE VALUE
Isoenzyme assays are performed to improve:
SPECIFICITY
What specimen preparation is commonly used to perform the alkaline phosphatase isoenzyme
determination?
SERUM IS DIVIDED INTO TWO ALIQUOTS, ONE IS HEATED AT 56C AND THE OTHER IS UNHEATED
As the temperature is increased from 25C to 37C in the GGT reaction, the activity of the reaction
IS DOUBLED
One method to enhance the differentiation of bone from liver alkaline phosphatase isoenzyme is to pretreat an aliquot of the sperm specimen.
BY HEATING AT 56C
Which of the following may be associated with
organophosphate poisoning?
CHOLINESTERASE
Which of the following may be associated with
macro-CK?
A AND C ARE BOTH CORRECT
In an adult, a normal serum Gamma Glutamyl
Transferase level with an elevated serum Alkaline phosphatase may be suggestive of:
BONE
DISEASE
Which of the following may be associated with the creatine kinase isoenzyme?
BOTH B AND C
ARE CORRECT
In pesticide poisoning, a decrease in enzyme
activity is associated with
CHOLINESTERASE
Which of the following is considered as a gold
standard test for growth hormone deficiency?
INSULIN TOLERANCE TEST
Composition of Thyroid stimulating hormone,
except:
GAMMA SUBUNITS
It is the regulator of adrenal and androgen
synthesis in human.
ACTH
The main stimulus for the uptake of iodide by the thyroid gland.
TSH
It indirectly mediates metabolic and anabolic
actions of growth hormone.
A AND C
Most abundant of all the pituitary hormones.
GROWTH HORMONES
Adult Growth hormone deficiency is due to:
PITUITARY ADENOMA
Cell of the Pituitary gland that secretes Prolactin.
LACTOTROPH
It is also Known as neurohypophysis.
POSTERIOR PITUITARY
