HEMA 2 QUIZ 2 Flashcards
The APTT is sensitive to a deficiency of which clotting factor?
A. Factor VII
B. Factor X
C. PF3
D. Calcium
Factor X
Which test result would be normal in a patient with dysfibrinogenemia?
A. Thrombin time
B. APTT
C. PT
D. Immunologic fibrinogen level
Immunologic fibrinogen level
A patient with a prolonged PT is given intravenous vitamin K. The PT corrects to normal after 24 hours. What clinical condition most likely caused these results?
A. Necrotic liver disease
B. Factor X deficiency
C. Fibrinogen deficiency
D. Obstructive jaundice
Obstructive jaundice
Which factor deficiency is associated with a prolonged PT and APTT?
A. X
B. VIII
C. IX
D. XI
X
A prolonged APTT is corrected with factor VIII– deficient plasma but not with factor IX–deficient plasma. Which factor is deficient?
A. V
B. VIII
C. IX
D. X
IX
Which of the following is a characteristic of classic hemophilia A?
A. Prolonged bleeding time
B. Autosomal recessive inheritance
C. Mild to severe bleeding episodes
D. Prolonged P
Mild to severe bleeding episodes
Refer to the following results:
PT = prolonged
APTT = prolonged
Platelet count = decreased
Which disorder may be indicated?
A. Factor VIII deficiency
B. von Willebrand’s disease
C. DIC
D. Factor IX deficiency
DIC
Which of the following is associated with an abnormal platelet aggregation test?
A. Factor VIII deficiency
B. Factor VIII inhibitor
C. Lupus anticoagulant
D. Afibrinogenemia
Afibrinogenemia
Refer to the following results:
PT = normal
APTT = prolonged
Bleeding time= increased
Platelet count = normal
Platelet aggregation to ristocetin = abnormal
Which of the following disorders may be indicated?
A. Factor VIII deficiency
B. DIC
C. von Willebrand’s disease
D. Factor IX deficiency
von Willebrand’s disease
Which results are associated with hemophilia A?
A. Prolonged APTT, normal PT
B. Prolonged PT and APTT
C. Prolonged PT, normal APTT
D. Normal PT and APTT
Prolonged APTT, normal PT
Which of the following is associated with multiple factor deficiencies?
A. An inherited disorder of coagulation
B. Severe liver disease
C. Dysfibrinogenemia
D. Lupus anticoagulant
Severe liver disease
Normal PT and APTT results in a patient with a poor wound healing may be associated with:
A. Factor VII deficiency
B. Factor VIII deficiency
C. Factor XII deficiency
D. Factor XIII deficiency
Factor XIII deficiency
Which of the following is a predisposing condition for the development of DIC?
A. Adenocarcinoma
B. Idiopathic thrombocytopenic purpura (ITP)
C. Post-transfusion purpura (PTP)
D. Heparin-induced thrombocytopenia (HIT
Adenocarcinoma
The following results were obtained on a patient: normal platelet count and function, normal PT, and prolonged APTT. Which of the following disorders is most consistent with these results?
A. Hemophilia A
B. Bernard–Soulier syndrome
C. von Willebrand’s disease
D. Glanzmann’s thrombasthenia
Hemophilia A
One of the complications associated with a severe hemophilia A is:
A. Hemarthrosis
B. Mucous membrane bleeding
C. Mild bleeding during surgery
D. Immune-mediated thrombocytopenia
Hemarthrosis
The most common subtype of classic von Willebrand’s disease is:
A. Type 1
B. Type 2A
C. Type 2B
D. Type 3
Type 1
A prolonged APTT and PT are corrected when mixed with normal plasma. Which factor is most likely deficient?
A. VIII
B. V
C. XI
D. IX
V
Which of the following clotting factors plays a role in clot formation in vitro, but not in vivo? in vitro clot formation and not in vivo coagulation?
A. VIIa
B. IIa
C. XIIa
D. Xa
XIIa
Which results would be expected for the prothrombin time (PT) and activated partial thromboplastin time (APTT) in a patient with polycythemia?
A. Both prolonged
B. Both shortened
C. Normal PT, prolonged APTT
D. Both normal
Both prolonged
What reagents are used in the PT test?
A. Thromboplastin and sodium chloride
B. Thromboplastin and potassium chloride
C. Thromboplastin and calcium
D. Actin and calcium chloride
Thromboplastin and calcium
Which test would be abnormal in a patient with factor X deficiency?
A. PT only
B. APTT only
C. PT and APTT
D. Thrombin time
PT and APTT
Hemophiliac father and the mother is heterozygous hemophilia, what could be the possible effect on the offspring
a. 50% chance of a normal offspring
b. 50% chance of a normal daughter
c. 50% chance of a normal son
d. 25% chance of a hemophiliac offspring
50% chance of a normal son
Which clotting factor is not measured by PT and APTT tests?
A. Factor VIII
B. Factor IX
C. Factor V
D. Factor XIII
Factor XIII
Which of the following characterizes vitamin K?
A. It is required for biological activity of fibrinolysis
B. Its activity is enhanced by heparin therapy
C. It is required for carboxylation of glutamate residues of some coagulation factors
D. It is made by the endothelial cells
It is required for carboxylation of glutamate residues of some coagulation factors
Which of the following clotting factors are measured by the APTT test?
A. II, VII, IX, X
B. VII, X, V, II, I
C. XII, XI, IX, VIII, X, V, II, I
D. XII, VII, X, V, II, I
XII, XI, IX, VIII, X, V, II, I
Which among the ff. will prolong PT result due to antagonism to Vit. K?
a. Bile duct obstruction
b. Newborn
c. Anbiotic
d. Brodifacoum
Brodifacoum
A heparin neutralizer
a. VIt K
b. Tissue factor
c. Polybrene
d. Antithrombin
Polybrene
Which among the ff. matches is incorrect?
a. PT is used to monitor warfarin therapy
b. PTT is used to monitor Unfractionated heparin therapy
c. 11-Dehydrothomboxane B 2 is used to monitor aspirin heparin
d. NOTA
NOTA
In BBL fibrometer, timer will stop
a. If the fibrin formed conducts electricity
b. If the fibrin formed moves the steel ball
c. If the fibrin formed reduce the movement of the steel ball
d. AOTA
If the fibrin formed conducts electricity
A jaundiced patient requested for coagulation study and yield shortened PT result, what is the next step to do?
a. Report the result
b. Proceed to SGPT, SGOT, and bilirubin analysis
c. Check if the instrument used is Photo optical, repeat test with electromechanical
d. Repeat the test
Check if the instrument used is Photo optical, repeat test with electromechanical
