Hem-Onc Cancer Drugs Flashcards by Jessica Martin | Brainscape

Q

Drugs that block M cell cycle

A

Vinca Alkaloids

Taxols

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Q

Drugs that block DNA Synthesis

A

Antimetabolites
Etoposide
Teniposide

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Q

Drugs that block G2

A

Bleomycin
Etoposide
Teniposide

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Q

Drugs that block G2

A

Bleomycin
Etoposide
Teniposide

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Q

MTX, 5-FU: mech

A

decrease thymidine synthesis

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Q

6-MP: mech

A

decreases purine synthesis

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Q

Alkylating agents, cisplatin: mech

A

cross-link DNA

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Q

Dactinomycin, doxorubicin: mech

A

DNA intercalators

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Q

Etoposide: mech

A

inhibits topoisomerase II

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Q

Hydroxyurea: mech

A

inhibits ribonucleotide reductase

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Q

Bleomycin: mech

A

DNA strand breakage

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Q

Irinotecan: mech

A

inhibits topoisomerase I

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Q

Vinca Alkaloids: mech

A

inhibit microtubule formation

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Q

Paclitaxel: mech

A

inhibits microtubule disassembly

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