Heavy metals chelating agents Flashcards
1
Q
Deferoxamine
A
Chelates (free) iron.
Toxic side effects pesent.
2
Q
Dimercaprol (BAL)
A
Chelates arsenic, mercury, and gold, lead (in children).
Side effects are present but not serious.
3
Q
DMSA (succimer, Chemet)
A
Chelates lead, mercury, and arsenic.
No known toxicities.
Oral administration.
4
Q
Penicillamine
A
Copper chelating agent (Wilson’s disease - hepatolenticular degeneration).
Also used for mercury, lead, and zinc poisoning.
Side effects: Allergic reaction, nephrotoxicity,
Oral administration.
5
Q
EDTA (CaNa2EDTA)
A
Lead chelating agent.
IV administration.
Nephrotoxicity.