Heavy metals chelating agents Flashcards

1
Q

Deferoxamine

A

Chelates (free) iron.

Toxic side effects pesent.

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2
Q

Dimercaprol (BAL)

A

Chelates arsenic, mercury, and gold, lead (in children).

Side effects are present but not serious.

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3
Q

DMSA (succimer, Chemet)

A

Chelates lead, mercury, and arsenic.
No known toxicities.
Oral administration.

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4
Q

Penicillamine

A

Copper chelating agent (Wilson’s disease - hepatolenticular degeneration).
Also used for mercury, lead, and zinc poisoning.
Side effects: Allergic reaction, nephrotoxicity,
Oral administration.

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5
Q

EDTA (CaNa2EDTA)

A

Lead chelating agent.
IV administration.
Nephrotoxicity.

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