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Pharmacology > Cardiology > Flashcards

Cardiology Flashcards

1
Q

Loop diuretics (they act on the thick part of the ascending limb of the loop of Henle)

A

Furosemide
Bumetanide
Torsemide

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2
Q

Thiazides (they act at the distal tubule, blocking reaborption of 3-5% of Na+)

A

(Diuretics)

HCTZ

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3
Q

K+ sparing Diuretics (they act at DCT and collecting duct)

A

Spironolactone

Eplerenone

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4
Q

Digoxin (digitalis)

A

(Inotropic)

Cardiac glycoside. Inotropic (HFrEF), supraventricular arrhythmia.

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5
Q

Sympathetomimetic amines (beta-adrenergic agonists)

A

Dopamine, Dobutamine, Isoproterenol, Epinephrine, Norepinephrine

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6
Q

Phosphodiesterase-3 inhibitor (second line Heart Failure Tx)

A

(Inotropic)

Milrinone

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7
Q

ADH-Vasopressin (IV)

A

Used for Peripheral vasoconstriction in vasodilatory shock.

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8
Q

ACE inhibitors

A

(Vasodilatory)
‘ - pril’
Captopril, Enalapril, Lisinopril, Ramipril, Trandolapril

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9
Q

ARB (Angiotensin-Receptor Blocker)

A

(Vasodilatory)
‘ - artan’
Losartan, Candesartan, Valsartan

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10
Q

Calcium-ion channel blocker

A

(Vasodilatory)
Verapamil
Dilitazem
Dihydropyridines (Nefidipine, Amlodipine, Felodipine)

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11
Q

Direct-Acting Vasodilators

A

Hydralazine
Minoxidil
Sodium nitroprusside
Fenoldopam

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12
Q

Organic Nitrates

A

(Vasodilatory)

Nitroglycerin

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13
Q

Natriuretic peptides

A

(Vasodilatory)

Nesiritide (synthetic BNP)

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14
Q

Phosphodiesterase - 5 inhibitor

A

(Vasodilatory)

Sildenafil

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15
Q

Alpha-1-adrenergic receptor antagonist (alpha blocker)

A 
Prazosin
Terazosin
Doxazosin
Phentolamine
Phenoxybenzamine
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16
Q

Alpha-2 agonists

A

Clonidine, Guanabenz, Alpha-methyldopa

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17
Q

Beta-blocker

A

Carvedilol, Metoprolol, Atenolol, Esmolol, Labetolol

18
Q

Procainamide and Quinidine

A

Class IA (fast Na+ channel blockers) Anti-Arrhythmic

19
Q

Lidocaine, Mexiletine

A

Class IB (fast Na+ channel blockers) Anti-Arrhythmic

20
Q

Propafenone, Flecainide

A

Class IC (fast Na+ channel blockers) Anti-Arrhythmic

21
Q

Class II Anti-Arrhythmic Drugs?

A

Beta-blockers (metoprolol, Esmolol, Propanolol)

22
Q

Amiodarone

A

Class III (K+ channel blocker) Anti-Arrhythmic

23
Q

Sotalol

A

Class III (K+ channel blocker) Anti-Arrhythmic

24
Q

Dofetilide

A

Class III (K+ channel blocker) Anti-Arrhythmic

25
Q

Ibutilide

A

Class III (K+ channel blocker) Anti-Arrhythmic

26
Q

Dronedarone

A

Class III (K+ channel blocker) Anti-Arrhythmic

27
Q

Class IV Anti-Arrhythmic Drugs?

A

Calcium channel blockers (non-dihydropiridine): Dilitazem, Verapamil

28
Q

Class III Anti-Arrhythmic Drugs?

A

K+ Channel blockers: Amiodarone, Sotalol, Ibutilide, Dofetilide, Dronedarone.

29
Q

Aspirin (COX inhibitor)

A

Anti-platelet drug

30
Q

Dipyridamole

A

Anti-platelet drug

31
Q

ADP receptor inhibitors

A 
(Anti-platelet drug)
Clopidogrel
Prasugrel
Triclopidine
Ticagrelor
32
Q

Glycoprotein IIb/IIIa

A

(Anti-platelet drug)
Abciximab
Eptifibatide
Tirofiban

33
Q

Anticoagulant drug

A

Warfarin, Heparin (UHF, LMWH - enoxaparin)

34
Q

Factor Xa inhibitor

A

Fondaparinux, Rivaroxiban, Apixaban, Edoxaban

35
Q

Direct Thrombin inhibitors

A

Dabigatran, Argatroban, Bivalirudin, Desirudin

36
Q

Thrombolytics / Fibrinolytic

A

Urokinae, Alteplase, Reteplase, Tenecteplase

37
Q

What vasodilatory drug causes lupus-like syndrome as a side effect ?

A

Hydralazine (direct acting arteriolar vasodilator)

38
Q

What vasodilatory drug causes CNS effects (blurred vision, nausea, as a side effect ?

A

Sodium nitroprusside (vasodilator)

39
Q

What vasodilatory drug causes peripheral edema as a side effect ?

A

Calcium channel blockers (mainly act on venous system)

40
Q

Which drugs are used to treat PHEochromocytoma (cathecholamine secreting tumor) ?

A

PHEnoxybenzamine, PHEntolamine (Alpha blockers)

Pharmacology (7 decks)

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