heart failure meds

Question 1

Beta blockers used in HF

Answer 1

metoprolol succinate
bisoprolol
carvedilol

Question 2

Metoprolol dosing

Answer 2

6. 25-12.5 mg/day

goal: 200mg/day

Question 3

Bisoprolol dosing

Answer 3

1.25mg/day

goal 10 mg/day

Question 4

Carvedilol dosing

Answer 4

3.125mg BID

goal is 25mg BID

Question 5

Lisinopril dosing

Answer 5

start w/5 mg
goal is 20mg

can dbl the dose every other week, if starting w/b-blocker have to alternate the titration, including starting (every other week will be up titrating either the b-blocker or the ACE/ARB)

Question 6

aldosterone blockers

Answer 6

spironolactone

eplirinone

Question 7

spironolactone dosing

Answer 7

12.5 - 25mg/day

Question 8

eplerenone dosing

Answer 8

25 mg/day

Question 9

vasodilators

Answer 9

hydralazine

isosorbide dinitrate

Question 10

loop dirutics

Answer 10

furosemide
bumetanide
torsemide

Question 11

furosemide dosing

Answer 11

10-40mg/day

Question 12

bumetanide dosing

Answer 12

.5-1 mg/day

Question 13

torsemide dosing

Answer 13

10-20 mg/day

Question 14

digoxin dosing

Answer 14

.125 mg/day

every other day in elderly

Question 15

nitroprusside

Answer 15

vasodilator acting directly on vascular smooth muscle,

Question 16

nitroglycerine

Answer 16

venous dilator, acts as nitric acid donor

Question 17

nesiritide

Answer 17

recombinant BNP
reduces sympathetic stimulation
inhibits renin-angiotensin-aldosterone system
results in vascular smoother muscle relaxation, balanced vasodilator and diuresis

Question 18

Dopamine

Answer 18

inotropic & vasopressor activities

converted to NE, activates alpha, beta, dopaminergic receptors

Question 19

Dobutamine

Answer 19

b-agonist

bind to beta 1 receptor and increases calcium influx during systole

Question 20

Milrinone

Answer 20

Phosphodiesterase inhibitor

increases intracellular cAMP whicn increases intracellular calcium