Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Asthma + COPD > Flashcards

Asthma + COPD Flashcards

1
Q

Asthma

A

Chronic inflammatory disorder, responsive to tirggers

airway inflamamtion contributes to airway hyperresponsiveness, airflow limitation

Reversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cellular Response of Asthma

A 
mast cell
eosinophils
neutrophils
T lymphocytes
macrophages
epithelial cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Presenting Symptoms

A

wheezing
cough worse at night
difficulty breathing
chest tightness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Asthma Dx

A

airflow obstruction is partially reversible on spirometry

increase of FEV1 greater than 200mL and greater than 12% from baseline measure after using short acting beta 2 agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Goal of therapy for asmtha

A

reduce impairment

require infrequent use of SABA (less than 2x/week)
maintain normal pulm fxn and activity levels

prevent–>exacerbations, er visits, loss of lung fxn

provide optimal pharacotherapy w/minimal effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

COPD onset

A

later in life

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

COPD etiology

A

cigarette smoke

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

COPD course

A

chronic, progressive (nonreversible)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Clinical Features of COPD

A

chronic cough/sputum, persistant worsening dyspnea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Inflammatory mediator for COPD

A

neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Inflammatory mediator for Asthma

A

eosinophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Nonpharm tx of COPD

A 
stop smoking
avoid triggers (cold air, pollutants)
filter air
adjust ADL's
diet
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

most common cause COPD exacerbation

A

infection and air pollution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Albuterol
Levabuterol
Pirbuterol

A

SABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ipatropium

A

Anticholinergic (short acting bronchodilator)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Combivent

A

SABA + Anticholinergic

17
Q 
Budesonide
Fluticasone
Mometasone
Ciclesonide
Beclomethasone
A

ICS

18
Q

Cromolyn

Nedocromil

A

Mast Cell Stabilizer

19
Q

Montelukast

Zafirlukast

A

LTRA

20
Q

Theophylline

A

Methylxanthine

21
Q

Salmeterol
Formeterol
Arformoterol
Indacaterol

A

LABA

22
Q

Vilanterol

A

combination LABA and corticosteroid
or
combination LABA and anticholinergic

23
Q

Tiotropium

Aclidinium

A

long acting bronchodilator (anticholinergic)

24
Q

Rofulmilast

A

oral PDE-4 enzyme inhibitor

Pharmacology (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions