Heart Failure Flashcards
syndrome in which heart is unable to meet metabolic needs of tissues despite adequate venous return
heart failure
severe ventricular dysfunction resulting in poor tissue perfusion and arterial hypotension
low output heart failure (“forward” HF, “cold”)
cardiac malfunction resulting in marked increased pulmonary venous and/or systemic venous pressures
congestive heart failure (“backward” HF, “wet”)
CO =
SV x HR
SV =
EDV-ESV
SV is regulated by what three things?
preload, afterload, contractility
Frank-Starling law explains what?
preload increases > SV increases (force of contraction)
afterload is largely determined by what?
degree of arterial and arterial constriction or dilation
when afterload increases, SV does what?
decreases (force of contraction decreases)
when contractility increases, SV does what?
increases
T/F: RAAS activation is a chronic response to decreased CO
TRUE (hrs-days)
what converts ang I to ang II?
ACE (from lungs)
increased vasopressin and endothelin I, free radicals, and increased thirst are all stimulated by what in the RAAS system?
angiotensin II
T/F: angiotensin II increases vasodilation and increases PSNS tone
FALSE, increases vasoCONSTRICTION and increases SNS tone
what is the effect of aldosterone on sodium ?
increased reabsorption > increased water reabsorption > increases blood volume (SV)