Heart & Cardiovascular system Flashcards

1
Q

What is systemic circulation?

A

supplies blood to & drains blood from the body.

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2
Q

What is pulmonary circulation?

A

transports blood to & from the lungs to receive oxygen.

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3
Q

Explain the lymphatic system, how it produces lymph, and how this returns.

A

At capillary beds blood is passing through, releasing a lot of plasma from the blood which bathes the cells, at this point it is called the interstitial fluid. Most of this makes its way back into the blood vessels. However, some of it is absorbed by lymphatic vessels, and produces what’s now called lymph - a filtrate of blood.
Network of drainage vessels for returning lymph to blood circulatory system.
Transports lymph via lymph nodes for ‘screening’ - immune response.

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4
Q

General S&F of arteries

A

Thick muscular wall
Narrow lumen
Carry high-pressure blood away from the heart.
Pulse

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5
Q

Detailed structure of arteries

A

3 layers called “tunica” (=coat):
Tunica intima
Inner layer
Thinnest as single layer of cells
Tunica media
Thickest layer
Lots of elastic fibres & smooth muscle
Elastic recoil → pulse
Tunica adventitia/externa
Outermost layer
Connective tissue
Anchors blood vessel

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6
Q

Role of capillaries

A

One cell thick, to shorten diffusion distance which maximises diffusion

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7
Q

General S&F of veins

A

Thin walled and floppy
Wide lumen
Carry low-pressure blood bac to heart
Valves to prevent backflow

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8
Q

Detailed structure of veins

A

Tunica intima
Inner layer
Thinnest – single layer of cells
Tunica media
Thinner than in arteries
Lots of elastic fibres & some muscles
Much stretchier than arteries
Tunica adventitia/externa
Outermost, thickest layer
Connective tissue
Anchors blood vessel

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9
Q

Explain the role of valves.

A

Veins have lower pressure than arteries
Valves needed to prevent backflow
Muscular contraction aid venous return
Negative pressure in thorax with inspiration ‘suck’ blood towards heart.

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10
Q

What is BP? How is it measured?

A

BP varies between systolic pressure (ventricles contracting) and diastolic pressure (heart relaxed and filling with blood)
Measured at brachial artery using a sphygmomanometer and stethoscope.

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11
Q

What are clinical pulses? How can they be measured?

A

Caused by elastic recoil of arteries
Can be palpated anywhere an artery can be compressed near the surface of the skin
Eg: Carotid pulse - neck, Radial pulse - felt at wrist in anatomical snuffbox

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12
Q

What are the layers of the pericardium?

A

Fibrous pericardium (outermost)
Strong fibrous layer
Firmly attached to diaphragm below
Attached in front to sternum
Fuses with outer layers of great vessels that pass into pericardium
Serous pericardium (middle 2 layers)
2 layers
Parietal - lines the fibrous pericardium
Visceral - closely covers heart
There is a small space between these layers called the pericardial cavity
This contains pericardial fluid (lubrication)

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13
Q

Explain role of RA

A

Receives DEOXYGENATED blood from body via SVC & IVC
Pectinate muscles, muscular ridges (only found in atria – mainly in RA)
Right auricle (remnant of fetal development)
SA & AV nodes
Fossa ovalis
Remnant of foramen ovale (hole) in atrial septum in fetal life
Opening for coronary sinus (coronary sinus drain coronary veins found in muscles of heart wall)
Tricuspid atrioventricular valve leading to right ventricle

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14
Q

Explain role of RV

A

Receives DEOXYGENATED blood from right atrium via tricuspid AV valve
Trabeculae carneae (only found in ventricles)
Muscular wall thicker than atria
Papillary muscles & chordae tendineae attach to valve leaflets
Prevent backflow of blood into atrium
Pulmonary semilunar valve leading to pulmonary trunk → pulmonary arteries to the lungs

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15
Q

Explain role of LA

A

Receives OXYGENATED blood from lungs via 4 pulmonary veins
Smooth-walled except for left auricle (pectinate muscles)
Fossa ovalis (more obvious in RA) (use to be a hole in interatrial septa)
Bicuspid (or mitral) atrioventricular valve leading to left ventricle

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16
Q

Explain role of LV

A

Receives OXYGENATED blood from left atrium via bicuspid AV valve
Trabeculae carneae (only found in ventricles)
Muscular wall much thicker than RV
Papillary muscles & chordae tendineae attach to valve leaflets
Prevent backflow of blood into atrium
Aortic semilunar valve leading to aorta

17
Q

Explain role of coronary arteries.

A

Supply the muscle of the heart
First branches of the aorta, though blood enters the right/left coronary artery from behind the leaflets of a valve, this is to ensure the high pressure blood does not damage the small coronary arteries.

18
Q

Explain role of coronary veins.

A

Drain blood from the muscle of the heart
Drain into RA via coronary sinus

19
Q

Explain the composition of cardiac muscle / myocardium

A

Involuntary striated muscle
Forms vast majority of the heart
Cardiac cells (cardiomyocytes) are contracting cells
Coordinate to produce normal heartbeat
Cells joined by intercalated discs to form long fibres (myofibrils)
Intercalated discs allow rapid electrical transmission, ensuring coordinated contraction
Many mitochondria for energy

20
Q

Explain the conduction system of the heart

A

Internal conduction system within the heart
Heart rate influenced by external signals:
Sympathetic innervation increases HR (fight or flight)
Vagus nerve (parasympathetic) slows HR (rest and digest)
Normal heart rhythm starts at sinoatrial node (SAN) - the ‘pacemaker’ of the heart
SAN initiates a wave of depolarisation which spreads into the atria causing simultaneous contraction. Non conductive tissue prevents direct spread to ventricles.
AVN stimulated by electrical wave, passing depolarisation onto Bundle of His, then to purkinje fibres based at the apex of the ventricle. These make the ventricles contract simultaneously from the bottom up for maximum efficiency.

21
Q

Define cardiac output

A

total blood vol pumped per unit time

22
Q

Define stroke volume

A

blood vol pumped by LV per heartbeat

23
Q

Define systole

A

contraction of the chambers of the heart

24
Q

Define diastole

A

relaxation of chambers of the heart

25
Q

What are the 5 stages of cardiac cycle?

A

1 - Relaxation (atrial and ventricular diastole)
2 - Ventricular filling
3 - Ventricular filling with atrial systole
4 - Ventricular contraction (ventricular systole)
5 - Ventricular ejection

26
Q

Explain what a P wave, QRS complex and T wave are.

A

P-wave = atrial systole
QRS complex = ventricular systole
T-wave = atrial & ventricular diastole

27
Q

What is the chest cavity divided into?

A

Lungs & pleura laterally
Mediastinum medially

28
Q

Where does the mediastinum extend to?

A

Root of neck (above)
Diaphragm (below)
Sternum (anteriorly)
Vertebral column (posteriorly)

29
Q

What are the 4 further divisions of the mediastinum?

A

Superior
Anterior
Posterior
Middle

30
Q

What is the azygos venous system?

A

Collateral circulation, draining upper lumbar region and posterior intercostal veins
Collateral circulation between SVC and IVC

31
Q
A