Healing & Repair Flashcards

1
Q

What are necrotic cells replaced with during repair?

A

Vital cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are two types of repair?

A
  1. Parenchyma regeneration

2. Fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: Parenchymal regeneration sometimes leaves no residual trace of injury

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What two components are needed for parenchymal regeneration to happen?

A
  1. Regeneration capacity

2. Maintains CT framework

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

T/F: Fibrosis results in a decrease in collagen w/in tissues

A

False; increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What the three types of cells based on regenerative capacity?

A
  1. Labile cells
  2. Stable cells
  3. Non-dividing/permanent cells
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are some consequences of fibrosis?

A
  1. Loss of functional parenchymal tissues

2. Alteration of physical properties of tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the hallmark of healing?

A

Granulation tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T/F: Proud flesh is due to exuberant granulation tissue

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the 4 zones of granulation tissue?

A
  1. Zone of necrotic debris and fibrin
  2. Zone of macrophages
  3. Zone of proliferation capillaries and fibroblasts
  4. Zone of mature fibrous CT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

T/F: Healing by first intention is when there is little exudate and tissues are close, while healing by second intention is when wound edges are widely separated

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the 9 general steps of skin healing?

A
  1. Blood clot
  2. Epithelial continuity restored
  3. Gradual covering
  4. Inflammation reaction develops
  5. Neovascularization
  6. Fibroblast proliferation
  7. Devascularization
  8. Egress of inflammatory cells and fibroblast regression
  9. Scar
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Massive hepatic necrosis is an example of healing for which specific tissue?

A

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which organ has limited regenerative capacity?

A

Kindney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What kind of appearance histologically does kidney repaired by regeneration have?

A

Flattened/ squamoid appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly