HDM Topics Flashcards
What is the first line treatment for SLE?
Plaquenil
What type of autoimmune rxn is:
Transplant rejection?
Type II
What are the primary sx for lupus?
Hx: Black people, women, pan-positive ROS
Sx: Recurrent flares, fatigue, arthralgia, weight loss, fever w/o focal infection, myalgia, malar rash (butterfly) or discoid rash (+ criteria), unexplained seizures (+), photosensitivity (+), Raynaud’s, mouth sores (+), pleuritic chest pain, abnormal ANA (+)
What type of autoimmune rxn is:
Serum sickness?
Type III
Arthus rxn.
What exam should you consider when you see a rash or nail pitting?
A joint exam.
What type of autoimmune rxn is:
PPD for TB?
Type IV
What is the typical presentation of RA?
Hx presentation: 30-50 y/o, women, smokers, FH of RA
Sx presentation: Pain and stiffness in multiple joints (especially wrists, PCP, and MCP), morning stiffness lasting more than 1 hour, fatigue, weight loss, anemia
Exam: Boggy swelling, synovial thickening in joint exam
Criteria
Have at least 1 joint with definite clinical synovitis
Synovitis not better explained by another disease
Low-high positive Rheumatoid factor or low-high positive ACPA
Abnormal CRP or abnormal ESR
>6 weeks
What should we check for in all children with arthritis?
Idiopathic inflammatory eye disease (Uveitis), should be screened by ophthalmologist in all children with arthritis
How does HIV often present?
Adults: Mono-like or flu like. Sore throat, malaise, fever.
Kids: SCID like, failure to thrive, diarrhea.
What are the treatments for psoriasis?
Mild (<5% body surface area)- Topical corticosteroids, Vitamin D, Tazorac
Moderate (~5% body surface area)- Systemic biologic therapiesn
Severe (>5% BSA) - TNF inhibitors for psoriatic arthritis
What type of autoimmune rxn is:
ABO mismatch?
Type II
What type of autoimmune rxn is:
Allergic contact dermatitis?
Type IV
What type of autoimmune rxn is:
Graves disease?
Type II
What is the most common type of B Cell disorder?
IgA deficiency
What type of autoimmune rxn is:
Myasthenia gravis?
Type II
