HD 11.09- All dermatology Flashcards
If the skin remains smooth and it is a raised surface, what sort of skin pathology is this?
Dermal pathology, also known as a HIVE
How would you describe the terms macule and patch?
Macule- little and flat skin lesion
Patch- big and flat skin lesion
How would you describe the terms papule, nodule and plaque?
Papule- little and raises skin lesion
Nodule- big and raised skin lesion
Plaque- big and raised but sticks out less
What is the difference between vesicles and bullae?
Vesicle- small fluid filled sac
Bulla- large fluid filled sac
Give an example of type 1 hypersensitivity and how to test for it?
Contact urticaria to rubber cloves
Anaphalaxis
IgE Mediated
Skin prick test
Give an example of type 4 hypersensitivity and how to test for it?
Allergic contact dermatitis
Patch testing
What are some signs of oral lichen planus?
Chronic autoimmune disease
PRESENCE OF DESQUAMATION AND ERYTHEMA/EROSION ON BUCCAL ASPECT OF ATTACHED GINGIVAE.
Can be induced by drugs/amalgam.
No sufficient treatment.
What are some signs of Lupus erythematosus (LE)?
Autoimmune disease (systemic) Oral lesions clinically resemble OLP 2 types Systemic lupus erythematosus (SLE) = BUTTERFLY LIKE RASH Discoid lupus erythematosus
Some oral signs of PEMPHIGUS VULGARIS?
Oral lesions precede skin lesions
I/O findings = mucosal erosion/ ulceration/ oral blister formation
Nikolsky’s sign = DESQUAMATIVE GINGIVITIS PRESENT + PRESSURE ON IT CAUSES A BLISTER
Most common skin cancer?
Basal cell carcinoma
Treated by excision.
3 drugs that cause lesions?
NICORANDIL • Potassium channel activator • Prescribed for acute coronary syndrome • Causes oral and skin ulceration • Oral ulcers painful with >1 occurrence • Managed via dose reduction OXYBUTYNIN • Lichenoid skin reaction • Difficult to differentiate from OLP CAPTOPRYL • May induce pemphigus vulgaris • ACE inhibitor – has sulfhydryl group