Hall Flashcards
Mixed venous O2 saturation equation
SvO2 = SaO2 - (VO2 / (1.39 * CO * Hgb)), VO2 = O2 consumption
Vital capacity is how many mL/kg
60-70 mL/kg, normal adult = 4500 mL
Carbon monoxide poisoning increases patient’s minute ventilation by what mechanism?
Causing lactic acidosis
Acute increase in PaCO2 of 10 mmHg will decrease pH by?
0.08 pH units
Total body deficit of bicarb
TBW * 24 - HCO3 * 0.3, TBW=Total Body Weight, 0.3 is extracellular fluid volume as a fraction of body mass
Compensatory decrease in bicarb for every 10 mmHg decrease of PaCO2
5 mEq/L for every 10 mmHg
Abnormal hemoglobins shift oxyhemoglobin dissociation curve in which direction
right shift
Transpulmonary shunt estimation with A-a gradient
1% shunt for each 20 mmHg of A-a gradient
Transpulmonary shunt equation
(CcO2 - CaO2) / (CcO2 - CvO2), oxygen content for end pulmonary capillary, artery, venous
What percentage of total body O2 consumption is used for work of breathing in normal resting adult
1-3%
Relationship between change of pH and [K+]
For every 0.08 unit change in pH is 0.5 mEq/L change in [K+]
A change in bicarb of 10 mEq/L will change pH by how much?
0.15 units of pH
Half life of carboxyhemoglobin in a pt breathing 100% O2
1 hour
signs of excessive cholinergic activity
DUMBELS - diarrhea, urination, miosis, bronchoconstriction, emesis, lacrimation, salivation
Best drug for treating hypotension in setting of severe acidemia
vasopressin, septic patients have relative deficiency of ADH
normal A-a gradient in normal awake pt breathing room air
5-10 mmHg
White count rises or decreases in TRALI?
neutropenia
newborn ACLS compression-ventilation ratio
90 to 30
elimination half time of amiodarone
29 days