Haemolytic Anaemia Flashcards
1
Q
Define haemolytic anaemia?
A
Premature destruction of RBCs
2
Q
What are common causes of haemolytic anaemia?
A
CONGENITAL
- Hereditary spherocytosis (autosominal dominant)
- Thalassaemia
- Sickle cell
- Glucose-6-phosphatase dehydrogenase (G6PD) deficiency (X-linked)
ACQUIRED
- Autoimmune haemolytic anaemia
- Microangiopathic haemolytic anaemia
- Infection
3
Q
What are the clinical features of haemolytic anaemia?
A
- Pallor
- Jaundice
- Splenomegaly
4
Q
What are the investigations for haemolytic anaemia?
A
BLOODS
- Unconjugated bilirubin +
- LDH +
- Reticulocyte count +
- Coombs’ test
BLOOD FILM
Polycaethemia
