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Haemotology > Disseminated intravascular coagulopathy > Flashcards

Disseminated intravascular coagulopathy Flashcards

1
Q

Define DIC?

A
  • Pathological activation of coagulation

- Results in bleeding and widespread microvascular thrombosis

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2
Q

What are the causes of DIC?

A

INFECTION
-gram -ve, meningococcal, viral

MALIGNANCY
-solid tumours, leukaemia

OBSTETRIC
-Eclapmsia, retained placenta, amniotic fluid embolus

IMMUNOLOGICAL
-Anaphylaxis

LIVER DISEASE
-Acute liver disease, cirrhosis

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3
Q

What are the symptoms of DIC?

A
  • Haemorrhage
  • Widespread microthrombi
  • Large vessel thrombosis
  • Haemorrhagic tissue necrosis
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4
Q

What are the investigations for DIC?

A 
BLOODS
-Platelets -
-PT/INR +
-APTT +
-Fibrinogen -
D-dimer ++
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5
Q

What is the management of DIC?

A
  • Treat underlying cause

- FFP, Platelets, Cryoprecipitate

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Haemotology (19 decks)

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