Haemoglobin and oxygen transport

Question 1

In the tense (T) configuration of Hb what is the affinity for oxygen

Answer 1

Low affinity

Question 2

In the relaxed (R) configuration of Hb what is the affinity for oxygen

Answer 2

Increased affinity

Question 3

is the O2 content and %saturation the same

Answer 3

no !

Question 4

What direction does the curve go with a decreased affinity

Answer 4

shifts to the right

Question 5

What does an increased temp do on oxygen saturation

Answer 5

Hb gives O2 up more readily and affinity decreases

Question 6

What does a decrease pH cause

Answer 6

decreased affinity and shift to the right

Question 7

What is the level of 2,3 DPG in stored blood

Answer 7

Low

Question 8

What happens to the curve if 2,3 DPG increases

Answer 8

decreases affinity and shift to the right

Question 9

What is Myoglobin

Answer 9

oxygen store in muscles

Question 10

What chain in Hb increases in terms of synthesis as you become and adult and decreases

Answer 10

Gamma chain decreases and Beta chain increases

Question 11

What is a source of error for pulse oximetry

Answer 11

Poor perfusion 
Motion 
Excessive light 
Venous pulsation 
Nail varnish 
Carbon monoxide

Question 12

What can sickle cell diseases cause

Answer 12

Occlusion of post capillary venule

Endothelial disfunction

Question 13

What vitamin is folate

Answer 13

B9

Question 14

What is folate responsible for

Answer 14

DNA synthesis of red blood cells

Question 15

What is B12 responsible for

Answer 15

Causes red blood cell to condense thus it isnt as small thus anemia can be bigger