Anaemia causes and types Flashcards
Dr Richard Byres
What organ produces EPO (erythropoietin)
kidneys in response to low O2
What does testosterone do to EPO (erythropoietin) production
enhances it
What does a haemoglobin molecule consist of
4 peptide chains (globin)
4 haem molecules
What is anaemia
reduction in haemoglobin haemoglobin
What is the haemoglobin concentration of anemia in men and women
Men < 13.5g/dl
Women <11.5g/dl
What are the 3 functional causes of anaemia
Blood loss
Impaired erythrocyte production
Excessive erythrocyte destruction
What can impair erythrocyte production
Iron Vitamin B12 Folate Protein Vitamin C
What chronic inflammation can cause erythrocyte production deficiencies
RA
What is Thalassaemia
Group of inherited disorders resulting in reduced production of one or more globin chains
What are the main types of thalassaemia
Beta Thalassaemia and Alpha Thalassaemia