Anaemia causes and types Flashcards

Dr Richard Byres

1
Q

What organ produces EPO (erythropoietin)

A

kidneys in response to low O2

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2
Q

What does testosterone do to EPO (erythropoietin) production

A

enhances it

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3
Q

What does a haemoglobin molecule consist of

A

4 peptide chains (globin)

4 haem molecules

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4
Q

What is anaemia

A

reduction in haemoglobin haemoglobin

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5
Q

What is the haemoglobin concentration of anemia in men and women

A

Men < 13.5g/dl

Women <11.5g/dl

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6
Q

What are the 3 functional causes of anaemia

A

Blood loss
Impaired erythrocyte production
Excessive erythrocyte destruction

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7
Q

What can impair erythrocyte production

A
Iron
Vitamin B12
Folate
Protein
Vitamin C
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8
Q

What chronic inflammation can cause erythrocyte production deficiencies

A

RA

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9
Q

What is Thalassaemia

A

Group of inherited disorders resulting in reduced production of one or more globin chains

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10
Q

What are the main types of thalassaemia

A

Beta Thalassaemia and Alpha Thalassaemia

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