Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Sem 2 Case 7 > Haematopoiesis > Flashcards

Haematopoiesis Flashcards

hey

1
Q

What is the largest component of the blood

A

Plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Haematopoiesis

A

process by which blood cells are formed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

life span of erythrocytes

A

120 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

life span of platelets

A

9-10 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where does Haematopoiesis take place in an adult

A

vertebrae, ribs, sternum,skull,sacrum,pelvis and proximal end of femur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In an infant where does Haematopoiesis take place in an infant

A

bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is red marrow made of

A

haematopoietic tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is yellow bone marrow made of

A

Fat cells

microenvironment of stroll cells and matrix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the CFU-GEMM also called

A

myeloid stem cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the order of making a mature erythrocyte

A 
Myeloid stem cell
Proerythroblast 
Erythroblasts
Normoblasts 
reticulocyte 
Mature erythrocyte (RNA lost)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the growth factor for red blood cells

A

Erythropoietin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is thrombopoiesis

A

production of platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What stimulates the production of platelets

A

Thrombopoietin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the process of production of megakaryoblasts

A

endomitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the largest WBC

A

Monocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the most abundant WBC

A

neutrophile

17
Q

What do Eosinophils protect against

A

parasites

18
Q

do all WBC have nucleus

A

yes bro

19
Q

where does GATA-1 differentiates cells

A

erythropoietic and megakaryocytic cell lineages

20
Q

where does PU.1 differentiate cells

A

myeloid lineage

21
Q

Erythropoietin (EPO)

A

Regulates erythropoiesis
Mainly synthesised in kidneys and liver
Reduction in red cell number results in decreased oxygen to tissues
Development of hypoxia in kidneys and liver
Leads to increased production of red blood cells
This corrects hypoxia and EPO synthesis switched off

22
Q

what does IL-3 help with

A

Works in conjunction with GM-CSF to proliferate most haemopoietic progenitor cells

23
Q

what does IL-5 help with

A

Plays a role in growth and differentiation of eosinophils

24
Q

where it Il-5 produced

A

T lymphocytes

Sem 2 Case 7 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions