Haemochromatosis Flashcards
1
Q
What is the definition of haemochromatosis?
A
Multisystemic disorder of dysregulated dietary iron absorption and increased iron release from macrophages
2
Q
What is the cause of haemochromatosis?
A
Autosomal recessive disorder
3
Q
What is the presentation of haemochromatosis?
A
Often incidental finding or prompted by diagnosis in family member
Fatigue, weakness, lethargy, arthralgias, hepatomegaly, diabetes, impotence, bronzing of skin
4
Q
What is the management of haemochromatosis?
A
Lifestyle modification - avoid iron or iron-containing supplements
Late stage - blood letting
5
Q
What are the complications of haemochromatosis?
A
Cirrhosis, diabetes, chronic CHF, hepatocellular carcinoma, hypogonadism, bone loss
