Autoimmune hepatitis Flashcards
1
Q
What is the definition of autoimmune hepatitis?
A
Chronic inflammatory disease of the liver of unknown aetiology
2
Q
What are the risk factors for autoimmune hepatitis?
A
Female, around age 45, other autoimmune condition
3
Q
What is the presentation of autoimmune hepatitis?
A
Fatigue, anorexia, abdominal discomfort, hepatomegaly, jaundice, pruritis, arthralgia, nausea, fever, spider angiomata
4
Q
What are the investigations for autoimmune hepatitis?
A
Raised AST, ALT, bilirubin, GGT, ALP, PTT
Consider antibodies
5
Q
What is the management for autoimmune hepatitis?
A
Corticosteroid, immunosuppressant
6
Q
What are the complications of autoimmune hepatitis?
A
Liver failure, cirrhosis, hepatocellular carcinoma, portal hypertension, oesophageal varices, ascites
