Haematopoiesis Flashcards

1
Q

What is haematopoiesis?

A

Production of red blood cells, white blood cells and platelets

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2
Q

Where does haematopoiesis occur?

A

Bone marrow

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3
Q

Which bones are active in haematopoiesis in children?

A

Most of the bones of the skeleton

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4
Q

Which bones are active in haematopoiesis in an adult?

A

Axial skeleton

  • skull
  • sternum
  • ribs
  • vertebrae
  • pelvis
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5
Q

When might a bone marrow biopsy/aspirate be taken?

A

Abnormal blood cell count

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6
Q

Where is a bone marrow biopsy/aspirate taken from?

A

Iliac crest

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7
Q

How do you look at the samples from a bone marrow biopsy/aspirate?

A

Under a microscope

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8
Q

What is the difference between a bone marrow biopsy and aspirate?

A

Biopsy - sample taken includes bone and bone marrow

Aspirate - sample taken includes bone marrow only

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9
Q

When would you choose a bone marrow aspirate over a biopsy?

A

When want to look at specific type of blood cells

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10
Q

How is haematopoiesis controlled?

A

Hormones

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11
Q

What stimulates erythropoiesis?

A

Erythropoietin

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12
Q

What stimulates thrombopoiesis?

A

Thrombopoetin

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13
Q

What stimulates granulocyte development?

A

G-CSF

granulocyte-colony stimulating factor

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14
Q

What stimulates lymphocyte development?

A

Interleukins

Tumour necrosis factors

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