Haematology

Question 1

Neoplasm whre the proliferation of abnormal haematopoeitc stem cells leads to scarring of marrow?

Answer 1

myelofibrisis

Question 2

possible severe complicaton of intensive chemotherapy in acute chemo

Answer 2

neutropenic sepsis

Question 3

Type of anaemia associated with folic acid deficiency?

Answer 3

Megaloblastic

Question 4

The most common heritable bleeding disorders?

Answer 4

von willebrand factor disease

Question 5

Lineage associated with production of erythrocytes

Answer 5

myleloid

Question 6

widespread activation of clotting cascade resulting in formation of micro clots in small vessels

Answer 6

disseminated
intravascular
coagulation

Question 7

Oral anticoagulant used to prevent thrombosis and thromboembolism

Answer 7

warfarin

Question 8

increase in no of RBCs

Answer 8

polycythaemia

Question 9

X linked recessive disorder resulting in factor8 deficiency?

Answer 9

haemophilia

Question 10

Malignant clonal proliferation of plasma cells

Answer 10

myeloma

Question 11

a lab technique where serum is placed on gel and exposed to an electric current

Answer 11

protein electrophoresis

Question 12

Tyrosine kinas inhibitor effective in CML

Answer 12

Imatinib

Question 13

Type of anaemia commonly resulting in a microcytic hpochromic picture?

Answer 13

iron deficiency

Question 14

Physiologoical development process that gives rise to cellular components of blood

Answer 14

haemopoiesis

Question 15

Possible treatment for young patients particularly with acute leukaemia

Answer 15

bone
marrow
transplant

Question 16

Type of anaemia with associated atrophic gastritis

Answer 16

pernicious

Question 17

Process of mixing a patients plasma with aliquots of donor rbc to see if therre is a reaction

Answer 17

crossmatching

Question 18

Neoplastic disorder of lymphoid tissue usually assoicated with t(14:18)

Answer 18

follicular lymphoma

Question 19

Granulocytes that often increase in parasitic infections and allergies

Answer 19

eosinophils

Question 20

Autosomal recessive disorder leading to defective alpha or beta globin chains?

Answer 20

thalassaemia

Question 21

Small red spots on the skin that dont blanch with pressure

Answer 21

petechiae

Question 22

Chromosomal abnormalitiy seen in CML?

Answer 22

philadelphia chromosome

Question 23

genetic blood disorder resulting in a rigid abnormally shaped red blood cell

Answer 23

Sickle cell disease

Question 24

Can be used to treat life threatening bleeding patients on warfarin

Answer 24

fresh frozen plasma

Question 25

Hormone that controls rbc production?

Answer 25

erythropoetin

Question 26

ORgan essential to the maintenance of normal levels if coagulation factors

Answer 26

liver