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Vet - notes > Haematology > Flashcards

Haematology Flashcards

1
Q

indications - erythrocytes

A

anaemia

erythrocytosis

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2
Q

indications - leukocytes

A

infl conditions
neoplastic conditions
chemotherapy

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3
Q

indications - platelets

A

bleeding disorders

DIC

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4
Q

indications - plasma

A

colour

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5
Q

Packed cell volume

A

allows buffy coat assessment
plasma - clear/straw or pink if haemolysed
total protein measurement

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6
Q

CBC - erythrocytes

A 
RBC conc
HGB - total haemoglobin
HCT - hematocrit + spun PCV
MCV - mean cell volume
MCH - mean cell haemoglobin
MCHC - mean cell haemoglobin conc
RDW - red cell distribution width
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7
Q

how to classify anemia

A

mild, moderate, severe
MCV - normo/micro/macrocytic
HCHC - normo/hyochromic (RBC conc)
regenerative or non

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8
Q

MCV - mean cell volume

A

average volume of a single cell

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9
Q

normocytic

A

RBCs of unremarkable size

often associated with mild non-regenerative anemia, acute haemorrhage

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10
Q

microcytic

A

red cell haemoglobin conc determines when division stops - Fe deficiency allows 1 more division - smaller RBCs
PSS, Fe deficiency, hepatic failure
akitas (breed)

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11
Q

macrocytic

A

in regeneration - polychromatophils larger the mature reds

some poodles

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12
Q

normo/hypochromic

A

haemoglobin conc
MCHC/MCH on panel
decreased in iron deficiency/poor iron incorporation

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13
Q

hyperchromic

A

not possible - haemolysis

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14
Q

regenerative anaemia

A

haemolysis

haemorrhage

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15
Q

non-regenerative anaemia

A

anaemia of infl/chronic disease
chronic renal failure
decreased production in marrow

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16
Q

reticulocytes

A

on diif-quik or giemsa stains young cells with ribosomal RNA show up larger, bluer cells - polychromatophils
same cells stained with new methylene blue and the RNA precipitates forming aggregates/reticulum - reticulocytes

17
Q

reticulocytes in cats

A

released as aggregate retics, mature to punctate retics over time

18
Q

RBC morphology

A 
spherocytes, ghost cells
hypochromasia/leptocytosis
shear products
oxidative damage
organisms
19
Q

components of a CBC (complete blood count)

A

total white blood cells (WBC)
neutro/eosino/basophils
lympho/monocytes

20
Q

leukocytes

A

normal - 100 cells/10x10*9/L

morphology - neutrophils - left shift, toxicity

21
Q

left shift classification

A

regenerative left shift - neutrophilia, segmented > bands

degenerative left shift - neutropenia, bands > segmented

22
Q

acute leukemias

A

blast cells in circulation
much more likely to be lymphoid
if signs of segmentation - myeloid, myelomonocytic
immunophenotyping - flow cytometer

23
Q

chronic leukemias

A

CLL - lymphocytes appear small, mature - persistent high numbers
CML - neutrophils appear normal - persistent high numbers

Vet - notes (32 decks)

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