H2-receptor antagonists

Question 1

Histamine H2-receptor antagonists heal (1?) and (2?) ulcers by reducing gastric acid output

Answer 1

1. Gastric

2. Duodenal

Question 2

What are the indications for the use of histamine H2-receptor antagonists? (4)

Answer 2

1. Gastric and duodenal ulcers
2. Relieve symptoms of GORD
3. Prophylactically to reduce the frequency of bleeding from gastroduodenal erosions in hepatic coma
4. Reduce risk of acid aspiration in obstetric patients at delivery

Question 3

Are H2-receptor antagonists normally used for the management of Zollinger-Ellison syndrome?

Answer 3

NO

PPIs are more effective

Question 4

Are H2-receptor antagonists beneficial in the management of haematemesis and melaena?

Answer 4

NO

But prophylactic use reduces the frequency of bleeding from gastroduodenal erosions in hepatic coma

Question 5

Prophylactic use of (?) reduce the frequency of bleeding from gastroduodenal erosions in hepatic coma

Answer 5

H2-receptor antagonsits

Question 6

Prophylactic use of H2-receptor antagonists reduce the frequency of (?) from gastroduodenal erosions in hepatic coma

Answer 6

bleeding

Question 7

Prophylactic use of H2-receptor antagonists reduce the frequency of bleeding from gastroduodenal erosions in (?)

Answer 7

hepatic coma

Question 8

In obstetrics, what is the use of H2-receptor antagonists?

Answer 8

Reduce the risk of acid aspiration at delivery (Mendelson’s syndrome)