H. pylori

Question 1

5 tests for H pylori

Answer 1

serology
urea breath
stool antigen
rapid urease
histology biopsy

Question 2

downsides/positives of serology

Answer 2

can be positive for antibodies w/o active infection, cant tell if its been eradicated

not affected by PPI use

Question 3

pros/cons of urea breath test

Answer 3

non invasive w/ good sensitivity and specificity, can sense active infection or not- used to document eradication

use of antibiotics or PPIs reduce efficacy

Question 4

process for rapid urease

Answer 4

sample of mucosa placed in well w/ urea and pH indicator

color change to pink w/ increase pH is a positive