GI Immunology Flashcards
1
Q
describe antigen uptake by GALT
A
M cells and dendritics sample antigens in peyers patch
2
Q
where are the most Ig secreting cells
A
GI tract
3
Q
how is IgA released from mucosal epithelium
A
plasma cells develop in peyers patch germinal centers, IgA secreted as dimer
dimer is modified by epithelial cells, secretory compenent added
4
Q
most common immunodeficiency
A
IgA deficiency
5
Q
describe oral tolerance
A
antigens do not provoke an immune response
6
Q
which wins out, T reg or pro inflammatory T cells?
A
T reg will win on balance, overall protective
7
Q
which part of the immune system helps protect bacteria from viruses
A
innate immune system
