H&N General Flashcards

1
Q

What percentage of all cancers in the US do H&N cancers account for?

A

H&N cancers account for nearly 4% of all cancers in the US.

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2
Q

What is the male to female ratio for H&N cancers?

A

The male to female ratio for H&N cancers is 2:1.

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3
Q

Which demographic is most affected by H&N cancers?

A

Non-Hispanic white individuals are most affected by H&N cancers.

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4
Q

What types of cancer are most commonly diagnosed in H&N cancers?

A

Most will be diagnosed with mouth, throat, or laryngeal cancer.

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5
Q

What is a major risk factor for head and neck cancer?

A

Smoking is a major risk factor for head and neck cancer.

All tobacco products, including cigarettes, cigars, pipes, and smokeless tobacco (chewing tobacco, snuff, or a type of chewing tobacco called betel quid) are linked to head and neck cancer.

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6
Q

How does alcohol consumption affect cancer risk?

A

Alcohol consumption raises the risk of getting cancers of the mouth, throat, and voice box.

This includes drinking any type of alcohol, such as beer, wine, or liquor.

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7
Q

What role does HPV infection play in head and neck cancers?

A

HPV infection is a risk factor, especially for oropharyngeal cancers.

Avoiding oral HPV infection can reduce the risk of HPV-associated head and neck cancers.

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8
Q

What vaccine has been approved for the prevention of HPV-related head and neck cancers?

A

The HPV vaccine Gardasil 9 has been granted accelerated approval for the prevention of oropharyngeal and other head and neck cancers caused by HPV.

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9
Q

What is a risk factor for nasopharyngeal cancers in Asia?

A

Epstein-Barr virus (EBV) infection is a risk factor for nasopharyngeal cancers in Asia.

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10
Q

What are some presenting symptoms of oral cavity cancers?

A

Symptoms include swelling, ulceration, and trismus.

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11
Q

What are the symptoms of oropharyngeal cancers?

A

Symptoms include dysphagia and otalgia.

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12
Q

What symptoms are associated with hypopharyngeal cancers?

A

Symptoms include dysphagia and swollen lymph nodes in the neck.

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13
Q

What are the symptoms of laryngeal cancers?

A

Symptoms include hoarseness, change in voice, and stridor.

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14
Q

What symptoms are related to nose/sinus cancers?

A

Symptoms include nasal obstruction, facial pain, and diplopia.

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15
Q

What are the symptoms of nasopharyngeal cancers?

A

Symptoms include epistaxis, difficulty hearing, otitis media, cranial nerve palsies, and headaches.

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16
Q

What are the symptoms of salivary gland cancers?

A

Symptoms include a painless mass and swelling under the chin.

17
Q

What are common symptoms of head and neck cancer?

A

Common symptoms may include a lump in the neck, a sore in the mouth or throat that does not heal and may be painful, a sore throat that does not go away, difficulty in swallowing, and a change or hoarseness in the voice.

18
Q

What should be done if an enlarged cervical node persists for 1 week or more in an adult?

A

It should be regarded as suspicious and evaluated for malignancy.

19
Q

What is important to do when experiencing symptoms of head and neck cancer?

A

It is important to check with a doctor or dentist about any of these symptoms.

20
Q

What are the methods for detection and diagnosis of head and neck cancer?

A

Methods include physical examination, endoscopy/laryngoscopy, fine needle biopsy, CT and MRI, PET, and chest X-ray.

21
Q

What does a fine needle biopsy confirm?

A

It confirms the presence of the tumor and its histologic type.

22
Q

What percentage of primary tumors can CT and MRI identify that show no clinical evidence on physical examination?

A

CT and MRI can identify up to 50% of primary tumors.

23
Q

What characteristics suggest metastatic disease in cervical nodes?

A

Nodes that are hard, greater than 1 cm, nontender, nonmobile, and raised suggest characteristics of metastatic disease.

24
Q

What should be considered for the overall accuracy of the pretreatment assessment?

A

Any diagnostic information that contributes to the overall accuracy should be considered.

25
Q

What is the most common origin of head and neck cancers?

A

Most head and neck cancers originate in mucous membrane epithelium, specifically squamous cell carcinoma (80%).

26
Q

How do head and neck cancers typically spread?

A

Head and neck cancers spread by direct extension, lymphatic spread, and hematogenous spread.

27
Q

What is the significance of lymph nodes in head and neck cancer?

A

The lymph nodes most commonly involved depend on the location from which the primary tumor arises.

28
Q

Where are most lymph nodes located in the neck?

A

Most lymph nodes are located along major blood vessels underneath the sternocleidomastoid muscle on each side of the neck.

29
Q

What staging systems are combined for head and neck cancer?

A

The staging is a combination of the AJCC and UICC TN system.

30
Q

What are the two types of staging in head and neck cancer?

A

CTNM is clinical staging, and pTNM is pathologic staging.

31
Q

What is the lymphatic drainage pattern in head and neck cancer?

A

Lymphatic drainage is mainly ipsilateral, but certain structures can have bilateral damage.

32
Q

What are some key lymph nodes involved in head and neck cancer?

A

Key lymph nodes include jugulodigastric, occipital, deep cervical, and supraclavicular nodes.

33
Q

What does the degree of cervical node involvement relate to?

A

The degree of cervical node involvement relates to prognosis.

34
Q

What is another name for the jugulodigastric node?

A

The jugulodigastric node is also known as the subdigastric node.

35
Q

What is the retroauricular node also known as?

A

The retroauricular node is also known as the mastoid node.

36
Q

Nearly ____ of the body’s entire lymph nodes are in the head and neck area.