Guillian Barre Flashcards
1
Q
What is Guillian Barre?
A
acute inflammatory demyelinating polyneuropathy
2
Q
What is the presentation?
A
A few weeks after an infection a symmetrical ascending muscle weakness starts
3
Q
What are some triggers for Guillian Barre?
A
campylobacter jejuni CMV mycoplasma zoster HIV EBV vaccinations
4
Q
What does the trigger cause?
A
antibodies that attack nerves
5
Q
what muscles are affected more?
A
proximal (unlike other neuropathies)
e.g. trunk, resp, cranial nerves
6
Q
What other symptoms can you get?
A
pain e.g. back, limb
autonomic dysfunction e.g. sweating, tachycardia, bp changes, arrthymias
7
Q
How is it diagnosed?
A
Clinical diagnosis
nerve conduction studies - slow conduction
LP
8
Q
What does the LP show?
A
high protein
normal WBC
9
Q
What is the treatment?
A
IV Ig
plasma exchange
