Guillain- Barre syndrome

Question 1

what is Guillain barre syndrome

Answer 1

immune mediated demyelination of peripheral nervous system often triggered by an infection

Question 2

initial symptoms of GB syndrome

Answer 2

back/leg pain

Question 3

characteristic features of GB syndrome

Answer 3

progressive symmetrical weakness of all the limbs
- weakness is ascending
reflexes are reduced or absent
sensory symptoms are mild
flaccid weakness and hyporeflexia

Question 4

investigations for GB syndrome

Answer 4

lumbar puncture: rise in protein and normal WCC
nerve conduction studies

Question 5

management of GB syndrome

Answer 5

Supportive care
VTE prophylaxis (pulmonary embolism is a leading cause of death)
IV immunoglobulins (IVIG) first-line
Plasmapheresis is an alternative to IVIG