gu: onset

Question 1

a-1 blockers onset

Answer 1

• symptom improvement 1-2 weeks for Tamsulosin
• may take up to 4 weeks for other drugs bc titration req
• urine flow may improve 4-8 hours after 1st dose

Question 2

a-1 blockers length of therapy

Answer 2

chronic

Question 3

a-1 blockers, incr dose if no improvement after

Answer 3

2-4 weeks (unless there’s SEs)

Question 4

5-a reductase inhib onset

Answer 4

• symptom improvement 6-12 months
• DHT levels reduced after 8 hours of admin
• significant reduction of prostate size takes months

Question 5

5-a reductase inhib length of therapy

Answer 5

chronic

Question 6

5-a reductase inhib, what to do if no improvement?

Answer 6

assess adherence before considering alt therapies

Question 7

Sildenafil duration

Answer 7

4 hours

Question 8

Tadalafil duration

Answer 8

36 hours

Question 9

Vardenafil duration

Answer 9

4 hours

Question 10

PDE5 inhib onset

Answer 10

30-60 minutes

can occur as soon as 10 min after prn dose

Question 11

do not take organic nitrate within __ of taking Sildenafil

Answer 11

24 hours

Question 12

do not take organic nitrate within __ of taking Vardenafil

Answer 12

24 hours

Question 13

do not take organic nitrate within __ of taking Tadalafil

Answer 13

48 hours

Question 14

anticholinergics onset

Answer 14

• symptom improvement 1-4 weeks
• max effect may take up to 12 weeks
• assess response at 4-6 weeks to determine therapy modications

Question 15

Phenazopyridine onset

Answer 15

1-6 hours

- Not all patients will experience adequate relief with phenazopyridine

Question 16

do not use Phenazopyridine for more than

Answer 16

2 days