CNS:classes Flashcards
1
Q
pharmacological treatment: depression
A
SSRIs, SNRIs, bupropion
2
Q
SSRIs
A
citalopram, escitalopram, fluoxetine, paroxetine, sertraline
3
Q
SNRIs
A
venlafaxine, duloxetine
4
Q
SSRIs MOA
A
block pre-synaptic reuptake of serotonin> incr concentration of serotonin in synapse
5
Q
SNRIs MOA
A
block serotonin and NE reuptake, weak inhibitors of dopamine (DA)
6
Q
pharmacological treatment: anxiety
A
- SSRIs, SNRIs for first line
- benzodiazepines (BZDs)
7
Q
BZDs MOA
A
- Binds to a separate site on the GABA receptor resulting in increased effectiveness of GABA
- Which produces a less excitable neuronal state (less anxiety, more sedation)
8
Q
BZDs
A
alprazolam, lorazepam, clonazepam, diazepam
9
Q
pharmacological treatment: insomnia
A
trazodone, Z-drugs
10
Q
Z-drugs
A
zolpidem, eszopiclone, zaleplon
11
Q
trazodone MOA
A
Serotonin modulator
12
Q
Z-drugs MOA
A
may bind to a different site on the GABA receptor, eliciting only sedation effects (and not anxiolytic effects)
