antivirals/fungals: MOA Flashcards
1
Q
oseltamivir MOA
A
Inhibits influenza virus neuraminidase to prevent release of virus from replication
2
Q
acyclovir MOA
A
Nucleoside analog; gets incorporated into the viral DNA→causing cell death & stops viral replication
3
Q
valacyclovir MOA
A
pro-drug of acyclovir
4
Q
fluconazole MOA
A
Inhibit ergosterol synthesis (inhibits particular P450)
→ Inhibit cell membrane formation
→ Fungal cell death
5
Q
nystatin MOA
A
Binds to ergosterol
→ Alter cell membrane permeability
→ Leakage of cellular contents
6
Q
terbinafine MOA
A
Inhibit ergosterol synthesis
→ Inhibit cell membrane formation
→ Fungal cell death
7
Q
ketoconazole MOA
A
Inhibit ergosterol synthesis (inhibits particular P450)
→ Inhibit cell membrane formation
→ Fungal cell death
