GU Flashcards
Most common pathogen causing UTI
E. Coli
Gram neg bacilli from the gut = 80%
1st line treatment for UTI
Course of tx?
Nitrofurantoin
M= 7-10d
F= 3d
Pts with comorbid conditions = 7-10d
What is the indication for phenazopyradine?
Anti-spasmodic- can be prescribed for UTI to prevent bladder spasm
SI- orange urine
Indication for fluvoxate?
Anti-spasmodic- prevent bladder spasm in UTI - makes urine bright orange
Who do you prescribe cephalosporins to with UTIs?
Reserve for pregnant ppl and Children
indication to follow-up with UTI
If blood present in the urine- ensure eradication with treatment to r/o cancer
Preferred medicine for OAB
Mirabegron
Post-menopausal women with OAB tx
Estrogen topical
Peasized amount in general genital area
Once daily x 2-4 wks
The twice weekly
Nitrites in urine indicate what?
Gram negative bacteria ie. ecoli
Causes of elevated BUN x4?
Low BUN?
Elevated- Renal Injury / high protein diet / hemolysis / CHF
Low- liver damage
What type of Casts in UA indicate:
Normal?
Infx?
Glomeural dysfunction?
N- Hyaline
Infx- WBC
Glomerular dx- RBC
Pt has a + Urine dip for protein. What is this measuring?
What should you order?
Albumin in urine——- NOT microambumin
Order 24h Urine
Causes of hematuria x5
Renal Colic
Cystitis
Pyelo
Cancer
Menses contam.
Treatment of Asymptomatic Bacteriuria
None EXCEPT Pregnant persons!
UTI’s in what population are more likely to become Pyelo
Children <3y & Pregnant person
Multiple bacteria on Urine C&S suggests what?
Sample contamination
Uncomplicated UTIs treatment
Septra (TMP/SMX) x 3d ——20% resistance rates
If likely resistant or allergic to sulfa-
Nitrofurantoin x 5d
What/ who are considered Complicated UTIs?
Considerations for treatment?
** Must treat for a minimum of 7d
Men
Children
Pregnant persons
Ppl with comorbid conditions
Immunocompromised
Recurrent UTI’s
Anatomical abnormalities
Recurrent UTI definition
F- >/= 3 per year or 2 in 6 months
Never normal in Males
R/o structural abnormalities/ other etiology
If UTI symptoms persist beyond 48-72 with abx treatment- what’s next?
Order C&S and UA
Change abx and extend course to 7 days
UTI definition (organism count)
> 100 000 CFU/mL of one organism
Pyelonephritis treated with Quinolones (ie. Ciprofloxacin or Levofloxacin) can be treated for ____ days
7 days = shorter
Describe Kidney position
Retroperitoneal at CVA
R is lower than L due to displacement by Liver
+++ Squamous epithelial cells in urine mean ?
Contamination
Normal WBC count?
Normal Neuts ?
WBC- 10.5
Neuts- > 80%
Presence of band or stabs in CBC indicate what?
Serious bacterial infx