Growth Factors Identified In The Endometrium

Question 1

Regulates extracellular matrix organization

Answer 1

Transforming growth factor (TGF-beta)

Question 2

Stimulates stromal cell differentiation regulates endometrial cell expression of integrins

Answer 2

Epidermal growth factor (EGF)

Question 3

Promotes mitosis and differentiation in the endometrium

Answer 3

Insulin-like growth factors (IGF-I and IGF II)

Question 4

Modulates trophoblast invasion

Answer 4

IGF binding protein-1 (IGFBP-1)

Question 5

Promotes angiogenesis, stimulates stromal cell proliferation

Answer 5

Platelet-derived growth factor (PDGF)

Question 6

Modulates angiogenesis and vascular permeability

Answer 6

Vascular endothelial growth factor (VEGF)

Question 7

Promotes mitotenic, angiogenic, inflammatory, and immunomodulatory effects

Answer 7

Tumor necrosis factor (TNF)

Question 8

Stimulates monocyte maturation, regulates mature macrophage cell function

Answer 8

Macrophage colony-stimulating factor (MCSF)

Question 9

Regulate proliferation and differentiation of granulosa cells as primary follicles grow

Answer 9

Growth differentiation factor 9 (GDF9)