Drugs In Pregnancy

Question 1

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women

Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester

Answer 1

PARACETAMOL, AMOXICILLIN, CEPHALEXIN

Question 2

Animal production studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Answer 2

PAROXETINE (antidepressants)

Question 3

There is no positive evidence if human fetal risk bases on adverse reaction data from investigational or marketing experience or studies humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Answer 3

PHENYTOIN, TETRACYCLINE, ASPIRIN

Question 4

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits

Answer 4

THALIDOMIDE, ISOTRETINOIN

Question 5

Adequate and well-controlled human studies have failed to demonstate a risk to the fetus in the first trimester of pregnancy (and there is no evidence if risk in later trimesters)

Answer 5

FOLIC ACID