Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PEDIA Y3 > Growth disorder > Flashcards

Growth disorder Flashcards

1
Q

Normal variants of short stature (2)

A

familial short stature

constitutional delay

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pathologic short stature EXCEPT

a. skeletal dysplasia
b. Constitutional delay
c. Psychosocial dwarfism
d. Chronic anemia

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Prenatal cause of short stature EXCEPT

a. IUGR
b. placental diseases
c. dysmorphic syndromes
d. endocrine disorders

A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q 
Cause of short stature when:
annual growth rate normal
height at or below 3rd percentile
no systemic or endocrine disease
pubertal growth at normal age
skeletal age equal to chronological age
ancestors relatively short
A

Familial short stature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Cause of short stature when
exaggerated “phase change” growth deceleration
transient deficiencies in GH secretion
severity of CDGP/BA delay reflects duration of periods of impaired GH secretion
slowed tempo of growth -> BA delay -> eventual pubertal delay
eventually reaches adult height/normal predicted adult height
normal at birth length

A

constitutional delay

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Lumbar lordosis
short extremtities
frontal bossing
normal intelligence

A

Achondroplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q 
bowed legs
stunted growth
large forehead
trouble sleeping
widening of wrists
A

Rickets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Small head
prominent beak-like nose
developmental delay
“bird headed dwarfism”

A

Seckel syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q 
hypertelorism
periauricular pit
developmental delay
small for age
short upper lip
short philtrum
cleft lip/palate
A

Wolf Hirschhorn syndrome; Greek warrior helmet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
upslanted eyes
low set ears
simian crease
gap bet 1st and 2nd toes
mental retardation
A

Trisomy 21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
Prominent occiput
micrognathia
low set ears
overlapping 4th and 5th fingers
rocker bottom feet
mental retardation
A

Trisomy 18

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q 
Microcephaly
microphthamia
cleft lip/palate
polydactyly
umbilical hernia
rocker bottom feet
A

Trisomy 13

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Physiologic effects of thyroid hormone:

Cardio

A

increased heart rate and CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Physiologic effects of thyroid hormone:

GI

A

increased gut motility; hyperthy - diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Physiologic effects of thyroid hormone:

Pulmo

A

maintenance of normal hypoxic and hypercapnic drive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Physiologic effects of thyroid hormone:

Neuromuscular

A

increased muscle protein turnover and increased speed of muscle contraction and relaxation

17
Q

Physiologic effects of thyroid hormone:

Lipids and Carbs in terms of hepatic gluconeogenesis and glycogenolysis and intestinal glucose absorption

A

increase

18
Q

Physiologic effects of thyroid hormone:

in terms of cholesterol synthesis and degradation

A

increase

19
Q

Physiologic effects of thyroid hormone:

in terms of lipogenesis

A

decrease

20
Q

Physiologic effects of thyroid hormone:

sympathetic nervous system - B adrenergic receptor in heart, skeletal muscle, lymphocytes;

A

increase

21
Q

Physiologic effects of thyroid hormone:

sympathetic nervous system: in terms of cardiac alpha-adrenergic receptors

A

decrease

22
Q

Physiologic effects of thyroid hormone:

in terms of catecholamine sensitivity

A

increase

23
Q

Physiologic effects of thyroid hormone:

Hematopoiesis

A

increase RBC, increase 2,3 DPG to increase oxygen availability to tissues

24
Q 
4 fingers with syndactyly
craniosynostosis
sunken appearance of face
bulging, wide set eyes
beaked nose
crowded teeth
A

Apert syndrome

25
Q

Anterior pituitary hormones (6)

A 
FSH
LH
TSH
ACTH
PRL
GH
26
Q

Posterior pitutary hormones

A

ADH

Oxytocin

27
Q 
Overgrowth disorder
developmental abnormalities
macroglossia
macrosomia
abdominal wall defects
renal abnormalities
ear pits/creases
A

Beckwith Wiedemann

28
Q 
Autosomal recessive
intellectual disability 
ectopia lentis downard
normal aorta
overgrowth
A

Homocystinuria

29
Q

Autosomal dominant
normal intelligence
ectopia lentis upward
aortic dilation

A

Marfan

30
Q

gigantism
excessive growth starts at infancy
autism, mild intellectual disability
NSD1 gene

A

Sotos syndrome

PEDIA Y3 (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions