Growth and Puberty Flashcards

1
Q

Quality and duration of p________ helps determine growth

A

pregancy

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2
Q

Growth = chondro_______

A

chondrogenesis

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3
Q

The hypothalamus produces ____ which stimulates GH from anterior pituitary

A

GHRH (growth hormone releasing hormone)

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4
Q

The hypothalamus produces ____ which inhibits GH from anterior pituitary

A

Somatostatin

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5
Q

Where does GH act to stimulate IGF-1 (insulin like growth factor 1)?

A

Liver

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6
Q

Which cells make GH in the anterior pituitary gland?

A

Somatotroph cells

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7
Q

What time is secretion of GH maximum?

A

At night

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8
Q

IGF-1 increases or decreases glucose use?

A

decreases

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9
Q

IGF-1 increases or decreases lipolysis?

A

Increases

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10
Q

IGF-1 increases or decreases muscle mass?

A

Increase

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11
Q

Puberty describes the p____________,
morphological, and behavioural changes
as the gonads switch from infantile to
adult forms.

A

Physiological

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12
Q

What is the name for first menstrual bleed?

A

Menarche

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13
Q

Ovarian and _______ androgens control pubic and axillary hair in girls

A

adrenal

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14
Q

Ovarian __________ regulate the growth of
breast and female genitalia

A

oestrogens

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15
Q

What regulates external genitalia and pubic hair growth and enlargement of larynx and laryngeal muscles (voice deepens)?

A

Testicular androgens

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16
Q

Precocious puberty is the onset of secondary sexual characteristics before _ years in girls, and _ years in boys

A

8 (girls)
9 (boys)

17
Q

Delayed puberty: absence of secondary sexual
characteristics by __ yrs (girl), __ yrs (boy)

A

14 (girls)
16 (boys)

18
Q

LH stimulates ______ cells to produce testosterone

A

Leydig cells

19
Q

FSH stimulates _______ cells to produce inhibin (negative feedback loop)

A

sertoli

20
Q

What stage of puberty is there increased stimulatory factors most prominently glutamate and kisspeptin

A

Start

21
Q

What stage of puberty is there decreased inhibitory tone mostly through GABAergic neurons secreting γ-aminobutyric acid (GABA) and opioidergic neurons

A

Start

22
Q

If a boy has early puberty (precocious) why is this a red flag?

A

Could have a brain tumour