Development of the Kidney and Urinary System Flashcards
What does the ureteric bud give rise to?
Collecting tubules, major and minor calyces, major and minor calyces, renal pelvis, ureter
What does the metanephric tissue give rise to?
Nephrons
What do the renal and genital systems develop from?
Intermediate mesoderm
What is the pronephros?
Non-functional, rudimentary part. Disappears by week 5.
What is the mesonephros?
Part that persists in males to make the vans deferens.
Develops in week 4
What forms the definitive kidney
Metanephros
When does the metanephros start to function?
12 weeks
When does the metanephros start to function?
12 weeks
What week does the metanephros develop?
5
Where does the metanephros develop?
Pelvic region
What does the collecting system develop from?
Ureteric bud (grows out from mesonephric duct, covered by a ‘cap’ of metanephric tissue. Bud grows into cap, renal pelvis)
The bud splits into 2 parts to form what?
The major calyces.
These continue to subdivide to form the tubules (ureter, renal pelvis, major and minor calyces, collecting tubules)
What does the excretory system develop from?
Metanephric cap
Metanephric tissue forms renal vesicles which become tubular and capillaries develop. This forms the…
glomerulus
Cloaca
Common cavity for urogenital system and the gut
What does the urorectal septum divide the cloaca into?
urogenital sinus and anal canal
The middle / pelvic part or urogenital sinus develops into
part of the urethra (prostastic part in males, paraurethra in females)
Phallic part of urogenital sinus develops into
Develops into penile urethra in males or vagina (?) in females
Where does the ureter develop from?
Ureteric bud
directly enters the bladder after the distal part of the mesonephric duct merges into the bladder wall.
The ureteric bud develops from the…
mesonephric bud
Early splitting of the ureteric bud results in
Double ureter
What is an ectopic ureter?
The ureter doesn’t drain into the bladder
Horseshoe kidney develops when the kidneys fuse at their
inferior poles
The fetal kidney ascends from the ___ to the ___
Pelvis to the abdomen