Growth and Development Flashcards

1
Q

What are some common measurement and assessment tools used to determine whether babies / children are developing normally?

A
  • Height (standing and sitting)
  • Length (babies)
  • Head circumference (<2 years old)
  • BMI
  • Bone age
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2
Q

What are some important practices when taking measurements of children during development?

A
  • Being accurate (use dots instead of crosses)

- Serial measurements: more data = easier analysis

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3
Q

What is bone age? What can it be used to predict?

A
  • The average age at which a child reaches a specific level of bone maturation. Usually equal to biological age but can be greater or lesser for those who hit early / late growth spurts

Bone age + height of a child can be used to predict adult height

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4
Q

What is another way to analyze the development of adolescents? Tools / criteria used?

A
  • Pubertal assessment
  • Tanner method (stages pubertal development according to breast development, pubic hair, axillary hair and genital development)
  • Prader Orchidometer (tool for measuring testicular volume)
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5
Q

Why is it hard to precisely define “normal development”?

A
  • Wide range (genetic diversity)
  • Differences in ethnic subgroups
  • Inequality in basic health and nutrition
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6
Q

What are the three important stages in normal growth? What rate of growth occurs at each?

A
  • Infantile: starts with a high rate of growth, decreases into childhood
  • Childhood: Rate of growth still slowly decreasing from highest infantile stage
  • Pubertal: Large spike in growth rate, decreases to zero into adulthood
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7
Q

Which gender reaches puberty earlier? What are the earliest signs of puberty based on gender?
Why are these signs important?

A
  • Females reach puberty earlier
  • Breast budding (tanner stage B2) in females
  • Testicular enlargement (Tanner stage G2) in males
  • Once these signs are present, usually confirms puberty will progress onwards
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8
Q

What are some indications for referral if growth disorder is suspected?

A
  • Extreme tall or short stature
  • Abnormal height change velocity
  • Obvious dysmorphic syndrome
  • Early / late puberty
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9
Q

What are some pathological causes of short stature?

A
  • Undernutrition
  • Chronic illness (JDA, IBD, Coeliac)
  • Iatrogenic (steroids)
  • Hormonal (GHD, hypothyroidism)
  • Syndromes (turner / P-W)
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10
Q

Signs of Growth Hormone Deficiency?

A
  • Child’s face appears younger
  • Short stature
  • Increased fat around face and stomach
  • Delayed puberty / tooth development
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11
Q

What can excess glucocorticoid exposure lead to?

A
  • Cushing’s syndrome

- Rapid weight gain can be seen in children with the condition

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12
Q

Developmental signs of Turner Syndrome?

A
  • Short stature
  • Thick neck tissue
  • Swollen extremities at birth
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13
Q

Developmental signs of Prader-Willi Syndrome?

A
  • Excessive weight gain
  • Short stature
  • Lack of genital development
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14
Q

Developmental signs of Noonan Syndrome?

A
  • Unusual facial features (drooping eyelids and wide distance between eyes, large forehead)
  • Short stature
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15
Q

Developmental signs of Achondroplasia?

A
  • Dwarfism
  • Small fingers
  • Limited range of motion at elbows
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16
Q

Most important pubertal stages in boys and girls? (Tanner stages)

A
  • B2 in girls

- G2 (T 3-4mL) in boys

17
Q

What is considered early and late puberty in boys?

A
  • Early < 9 years

- Late > 14 years (more common)

18
Q

What is considered early and late puberty in girls?

A
  • Early < 8 years

- Late >13 years (more common)

19
Q

What is GDGP? Which gender is it more common in? Signs?

A
  • Constitutional Delay in Growth and Puberty, usually resumes after delay period
  • More common in males
  • Short stature
  • Delayed puberty
20
Q

List some causes of delayed puberty

A
  • Gonadal dysgenesis (Turner / Klinefelter)
  • Chronic Disease (Crohn’s, Asthma)
  • Impaired HPG axis
21
Q

What does the term menarche refer to?

A
  • First occurrence of menstruation
22
Q

What is Central Precocious Puberty? List some signs

A
  • Early onset puberty

Signs:

  • Breast development at an early age
  • Testicular enlargement in boys
  • Growth spurts
  • Advanced one age
23
Q

What are some investigations for Central Precocious Puberty? Treatment?

A
  • MRI head: look for brain tumour / pituitary abnormalities

- GnRH antagonist

24
Q

What is Precocious Pseudopuberty? Signs?

A
  • Partial pubertal development resulting from autonomous (Gonadotropin independent) secretion of sex hormones
  • Early development of secondary sexual characteristics (but not sperm)