Growth

Question 1

what teeeam?

Answer 1

wilcats

Question 2

define:

• precoscious puberty

- pubertal delay

Answer 2

-normal pubertal development occurring abnormally early

Question 3

approach to groth problem

• Hx
• examination
• investigations

Answer 3

-ICE, birth, PMH, Pubertal symptoms, FH (height and puberty)

-height, weight, height velocity
pathological signs
pubertal status

-Bloods: gonadotrophins, growth factors, testosterone/oestrodiol, thyroid, karyotype 
bone age 
dynamic function tests
MRI brain
US uterus

Question 4

define:

• genetic short stature

- constitutional growth delay

Answer 4

-healthy child wont inherited short stature, no underlying endocrine abnormality & normal bone age

-late maturation causing short stature
present around puberty with delayed maturation and bone age

Question 5

Give 3 other reasons a child may have short stature and examples

Answer 5

dysmorphic syndromes: Down’s syndrome, Turner syndrome, fragile X syndrome

Endocrine disorders: hypothyroidism

chronic disease: asthma, coeliac and IBD

Question 6

weight centime for child to be considered:

• overweight
• obese
• endocrine causes of childhood obesity (8)
• inherited disorders that cause obesity (4)

Answer 6

• 91st centile
• 98th centile

-hypothryoidism
GH deficiency
Hypopituitarism
Hypogonadism
hypogonadotrophic hypogonadism
excessive corticosteroid
pseudohypoparathyroidism
craniopharyngioma

-Down’s syndrome, DMD, Prader willi syndrome, Fragile X