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group 21 to 25 Flashcards

1
Q

what is immunovant

A

clinical stage immunology company

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2
Q

what is immunovant platform

A

targeted monoclonal antibodies

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3
Q

what is acelyrin

A

late stage clinical biopharma company

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4
Q

what does acelyrin do

A

identifying, aquiring and accekerating the development and commercialization of medecines for diseases related to excess activation of the immune system

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5
Q

what is apogee

A

clinical stage biotech

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6
Q

what is apogee therapeutics platform

A

engineered monoclonal antibodies (mAbs) with potential best-in-class profiles to overcome current therapy limitations by optimizing
half-life, maximizing antibody recycling, and decreasing the dosing for patients.

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7
Q

what is tourmaline

A

late stage clinical biotech

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8
Q

what is tourmaline platform

A

focused on developing drugs to improve immune and inflammatoty diseases to set up new standards care for unmet medical needs

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9
Q

what is vir biotech

A

makes antiviral treatmnets

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10
Q

what is the platform of vur biotech

A

-Monoclonal antibody platform with AI-led protein engineering capabilities
○ T cell-based viral vector platform (Induce T cell response with engineered HCMV)
○ siRNA (in combination with antibodies)

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11
Q

what is atea pharmaceuticals

A

clinical stage biotech company commited to the discovert, development and commercialization of orally availabel direct acting antiviral therapies

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12
Q

what is the atea platform

A

Nucleus(t)ide analogs and prodrugs targeting RNA-dependent RNA polymerase of
+ssRNA viruses (mainly COVID-19, HCV, Dengue but were previously working on an RSV
drug).

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13
Q

what is regeron

A

Leading biotechnology company founded and led by physician-scientists whose medicines and pipelines are designed to
treat a variety of serious diseases such as eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and
metabolic diseases, hematologic conditions, infectious diseases, and rare diseases

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14
Q

what is regeneron platform

A

fully human therapeutoc antibodies and bispecific antibodies aka velocisuite tech

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15
Q

what is anapsdybio

A

o is a clinical-stage biotechnology company working to transform patient health by delivering innovative
immunology therapeutics with a focus on addressing unmet medical needs in autoimmune and inflammatory diseases.

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16
Q

what is anaptysbio platform

A

Coupling mammalian cell surface display with somatic hypermutation (SHM) for the discovery and maturation of
human antibodies

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17
Q

what is ovid therapeutics

A

clinical stage biopharmaceutical comp

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18
Q

what is ovid theraoeutics platform

A

small molecules trating the symtoms of epilepsy and other cns disorders

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19
Q

what is wave life sciences

A

s a biotechnology company which pioneers in transformative RNA medicines

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20
Q

what is wave life sciences platform

A

PRISMTM is an oligonucleotide platform combining four RNA-targeting modalities (editing, splicing, siRNA and antisense).

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21
Q

what is denali therapeutics

A

Clinical-stage biopharmaceutical company focusing on treatment of neurodegenerative
and lysosomal storage diseases.

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22
Q

what is the platform of debali therapeutics

A

Proprietary antibody transport vehicles (ATVs) and enzyme transport
vehicles (ETVs) with engineered BBB receptor binding into an Fc domain (Transferrin
receptor, TfR, highly expressed) thus actively transporting molecules across the BBB
through receptor-mediated transcytosis (RMT).

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23
Q

what is pic therapeutics

A

clinical stage biopharmaceutica company

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24
Q

what is pic therapeutics platfoem

A

small molecules that modify splicing, ferroptosis and inflammation

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25
what is agios pharmaceutical platform
Mitapivat - first-in-class oral small molecule acts as an allosteric activator for the Pyruvate kinase (PK) enzyme, enhancing its function. By binding allosterically, it boosts enzyme activity, leading to increased ATP production and reduced 2,3-diphosphoglycerate levels. Consequently, this results in an extended lifespan for red blood cells (RBCs).
26
what is keros therapeutics
clinical stahe biopharma
27
what is the platform of keros
Main focus on leveraging protein engineering, specifically working on the transforming growth factor-beta (TGF-β) superfamily to develop large and small molecule treatments. Use a proprietary library of ActRII Ligand traps.
28
what is beam therapeutics
clinical stage biopharmaceutical
29
what is beam therapeutics platform
Pioneering precision genetic medicine via gene editing/delivery technologies to address unmet medical needs for patients affected by Sickle Cell Disease (SCD), T-Cell Cancers, Glycogen Storage Disease 1a (GSD1a), Alpha-1 Antitrypsin Deficiency (AATD) & other rare and serious diseases
30
what is editas medecine platform
CRISPR - “Clustered, Regularly Interspaced, Short Palindromic Repeats,” can edit nearly any location in the genome in any cell or tissue, highly specific ○ Use two different proprietary CRISPR nucleases: SaCas9 and AsCas12a
31
what is arvinas
preclinical biotech
32
what is the platform of arvinas
PROTAC, Proteolysis Targeting Chimeric protein degraders, directs the protein proteasome to specifically destroy disease causing proteins, especially cancer and neurodegenerative diseases. PROTAC are composed of 2 binding regions (BR) connected by a linker, the targeted protein BR and the E3-ligase BR.
33
what is bicycle therapeutics platform
Development of Bicycle Toxin Conjugates (BTCs) and Bicycle Tumor-Targeted Immune Cell Agonists (TICAs).
34
what is kymera
clinical stage biotech
35
what is kymera platform
-targeted protein degradation -pegasus platform for dryg developmnet for discovert and development of therapies based on targeted protein degradation
36
what is nurix
Clinical Stage biopharmaceutical company using DEligase platform to discover and develop small molecule drugs to provide first-in class therapies for the unmet needs of patients with cancer and inflammatory diseases. -they do targeted protein degraders
37
what is the platform of nurix
: The DEligase platform enables the discovery of potent binders to difficult-to-drug ligase targets with good physicochemical properties. ❖ WIPO Patent Scope search reveals Nurix has 139 applicants on US fillings.
38
what is decipjera biopharmaceutival
commercial stage biopharmaceutical that focuses on switch control kinase inhibitor platfrom targeting various kinases involved in cancer and inflammatory diseases
39
what is deciphera biopharmaceuticals platform
proprietary tech focusing on switch control kinase inhibition to target a broad range of kinase mutations and combat cancer mutational resistance
40
what is kryslal biotech
commercial stage biopharmaceutical company
41
what is the platform of krystal biotech
engineered replication deficient hsv-1
42
what is incyte corporation
biopharmaceutical company
43
what is the incyte corporation platform
clinical programs of myeloproliferatobe neoplasms, graft versus host diseases, general hematology and oncology, dermatology with a focus on JAK inhibitors
44
what is iteos therapeutics
clinical stage biopharmaceutical company
45
what is the platform of iteos
highly differenciated immuno oncology treatments
46
what is Syndax Pharmaceuticals?
clinical stage biopharma company focusing on small molecule onhibitors and monoclonal antibody treat,ents
47
what is exscientia plc
clinical stage biopharmaceutical company developing small molecule drugs with an internal focus on oncology
48
what is the tech od exscientia plc
AI-driven drug discovery platform (Centaur Chemist) for quicker target identification, better molecular designs (efficacy, safety, bioavailability) and more-sensitive biophysical screening techniques of oncogenic factors.
49
what is prime medecine
preclinical stage biotech
50
what is the platform of prime medecine
gene editing aka prime editing
51
what is 4dmt
bio pharma company at clinical stage
52
what is the platform of 4dmt
therapeutics vector evolution: make aav vectors for gene delivery of targeted therapied
53
what is uniqure
clinical stage and pre clinical company focusing on the development og gene therapoes for rare diseases
54
what os the platform of uniqure
-aav based vector delivery system -gene cassette
55
what is verve therapeutcs
clinical stage biopharma for atherosclerotic cardiovascular disease
56
what is verve therapeutocs platform
single course in vivo base editing tech combines with novel lipid nanoparticle delivery system
57
what is rocket pharmaceuticals
clinical stage biotech company focused on developing first in class gene therapies for cardiovascular and he,atology based henetic diseases
58
what is rocket pharma platform
lentiviral virus and adeno associated virus aka aav gene therapies for rare genetic diseases
59
what is kalvista
focus on discovery, development and commercialization or oral, small molecule protease inhibitors for diseases with unmet needs
60
what is biocryst
Late-stage biotech developing small-molecule and protein therapeutics for complement-mediated and other rare diseases
61
what is biocryst platfprm
● Small-molecule and protein therapeutics ● Focus on developing easy to use medications ● Structure-guided drug design using atomic level predictive modeling and protein crystalization
62
what is argenx se
clinical stage biooharma
63
what is the platform fo argenx se
argenx simple antibody platform for discovery/development of therapeutic antibodies with enhanced propertties
64
what is adaptive biotech
commercial stage biotech
65
what is adaptibe tech platform
cutting edge immune medecine platform for immune diseasses
66
what is scholar rock
clinical stage biotech compa
67
what is scholar rock platform
Platform: monoclonal antibody development ● Technology and IP: targets growth factors to modulate their effects in tissues to treat spinal muscular atrophy, obesity, solid tumors, fibrosis, and anemia.
68
what. isolema pharma
Clinical stage biopharmaceutical company using endocrine therapies to create targeted therapies for women’s cancers with a focus on ER+HER2- metastatic breast cancer
69
what is humacyte
clinical stage biotech specializing in the dev and manifacturing of human acellular vesseslswhat
70
what is the platform of humacyte
-bioengineered human tissue: absorbable scaffold where tissue creating cells for vesseld formation followed by cell removal for implantation use
71
what is protagonist ther[
clinical stahe biopharma
72
what is protagonist therp platform
peptide tech platform , they have developped a pipeline of peptide and small molecule compounds that mimic or inhibit therapeuticallt relevant protein and protein interactions
73
what is crispr therapeutocs
Biotechnology company that focuses on gene editing using CRISPR Cas9 to treat serious diseases
74
what. isplatform for crispr therapeutcis
crispr cas bitch
75
what is blu bird bio
A biotechnology company committed to researching, developing, and commercializing potentially curative gene therapies for severe genetic diseases based on our proprietary lentiviral vector (“LVV”) gene addition platform
76
what is blubird bio platform
Proprietary lentiviral vector (“LVV”) gene addition platform; bluebird bio’s investigational gene therapies are manufactured with a patient’s own hematopoietic – or blood – stem cells. Functional copies of a gene are delivered to a patient’s stem cells using a delivery system called a “vector.”
77
what is arcturus therapeutic
A mRNA medicine and vaccine company that focuses on the discovery, development and commercialization of vaccine and rare diseases therapeuticsw
78
what is arcturus platform
LUNAR® lipid-mediated delivery and STARR™ (Self-amplifying) mRNA Technology
79

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