Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Business of science > group 21 to 25 > Flashcards

group 21 to 25 Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

what is immunovant

A

clinical stage immunology company

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is immunovant platform

A

targeted monoclonal antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is acelyrin

A

late stage clinical biopharma company

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what does acelyrin do

A

identifying, aquiring and accekerating the development and commercialization of medecines for diseases related to excess activation of the immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is apogee

A

clinical stage biotech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is apogee therapeutics platform

A

engineered monoclonal antibodies (mAbs) with potential best-in-class profiles to overcome current therapy limitations by optimizing
half-life, maximizing antibody recycling, and decreasing the dosing for patients.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is tourmaline

A

late stage clinical biotech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is tourmaline platform

A

focused on developing drugs to improve immune and inflammatoty diseases to set up new standards care for unmet medical needs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is vir biotech

A

makes antiviral treatmnets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the platform of vur biotech

A

-Monoclonal antibody platform with AI-led protein engineering capabilities
○ T cell-based viral vector platform (Induce T cell response with engineered HCMV)
○ siRNA (in combination with antibodies)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is atea pharmaceuticals

A

clinical stage biotech company commited to the discovert, development and commercialization of orally availabel direct acting antiviral therapies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the atea platform

A

Nucleus(t)ide analogs and prodrugs targeting RNA-dependent RNA polymerase of
+ssRNA viruses (mainly COVID-19, HCV, Dengue but were previously working on an RSV
drug).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is regeron

A

Leading biotechnology company founded and led by physician-scientists whose medicines and pipelines are designed to
treat a variety of serious diseases such as eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and
metabolic diseases, hematologic conditions, infectious diseases, and rare diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is regeneron platform

A

fully human therapeutoc antibodies and bispecific antibodies aka velocisuite tech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is anapsdybio

A

o is a clinical-stage biotechnology company working to transform patient health by delivering innovative
immunology therapeutics with a focus on addressing unmet medical needs in autoimmune and inflammatory diseases.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is anaptysbio platform

A

Coupling mammalian cell surface display with somatic hypermutation (SHM) for the discovery and maturation of
human antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is ovid therapeutics

A

clinical stage biopharmaceutical comp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is ovid theraoeutics platform

A

small molecules trating the symtoms of epilepsy and other cns disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is wave life sciences

A

s a biotechnology company which pioneers in transformative RNA medicines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is wave life sciences platform

A

PRISMTM is an oligonucleotide platform combining four RNA-targeting modalities (editing, splicing, siRNA and antisense).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what is denali therapeutics

A

Clinical-stage biopharmaceutical company focusing on treatment of neurodegenerative
and lysosomal storage diseases.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what is the platform of debali therapeutics

A

Proprietary antibody transport vehicles (ATVs) and enzyme transport
vehicles (ETVs) with engineered BBB receptor binding into an Fc domain (Transferrin
receptor, TfR, highly expressed) thus actively transporting molecules across the BBB
through receptor-mediated transcytosis (RMT).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is pic therapeutics

A

clinical stage biopharmaceutica company

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what is pic therapeutics platfoem

A

small molecules that modify splicing, ferroptosis and inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

what is agios pharmaceutical platform

A

Mitapivat - first-in-class oral small molecule acts as an allosteric activator for the Pyruvate kinase (PK) enzyme, enhancing its
function. By binding allosterically, it boosts enzyme activity, leading to increased ATP production and reduced 2,3-diphosphoglycerate
levels. Consequently, this results in an extended lifespan for red blood cells (RBCs).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

what is keros therapeutics

A

clinical stahe biopharma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

what is the platform of keros

A

Main focus on leveraging protein engineering, specifically working on the transforming growth factor-beta (TGF-β) superfamily to
develop large and small molecule treatments. Use a proprietary library of ActRII Ligand traps.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

what is beam therapeutics

A

clinical stage biopharmaceutical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

what is beam therapeutics platform

A

Pioneering precision genetic medicine via gene editing/delivery technologies to address unmet medical needs for patients affected by Sickle Cell Disease
(SCD), T-Cell Cancers, Glycogen Storage Disease 1a (GSD1a), Alpha-1 Antitrypsin Deficiency (AATD) & other rare and serious diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

what is editas medecine platform

A

CRISPR - “Clustered, Regularly Interspaced, Short Palindromic Repeats,” can edit nearly any location in the genome in any cell or tissue, highly specific
○ Use two different proprietary CRISPR nucleases: SaCas9 and AsCas12a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

what is arvinas

A

preclinical biotech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

what is the platform of arvinas

A

PROTAC, Proteolysis Targeting Chimeric protein degraders, directs the protein proteasome to specifically destroy disease
causing proteins, especially cancer and neurodegenerative diseases. PROTAC are composed of 2 binding regions (BR) connected by a linker, the
targeted protein BR and the E3-ligase BR.

33
Q

what is bicycle therapeutics platform

A

Development of Bicycle Toxin Conjugates (BTCs) and Bicycle
Tumor-Targeted Immune Cell Agonists (TICAs).

34
Q

what is kymera

A

clinical stage biotech

35
Q

what is kymera platform

A

-targeted protein degradation
-pegasus platform for dryg developmnet for discovert and development of therapies based on targeted protein degradation

36
Q

what is nurix

A

Clinical Stage biopharmaceutical company using DEligase platform to discover and develop small molecule drugs to provide first-in class therapies for the unmet needs of patients with cancer and inflammatory diseases.
-they do targeted protein degraders

37
Q

what is the platform of nurix

A

: The DEligase platform enables the discovery of potent binders to difficult-to-drug ligase targets with good physicochemical properties.
❖ WIPO Patent Scope search reveals Nurix has 139 applicants on US fillings.

38
Q

what is decipjera biopharmaceutival

A

commercial stage biopharmaceutical that focuses on switch control kinase inhibitor platfrom targeting various kinases involved in cancer and inflammatory diseases

39
Q

what is deciphera biopharmaceuticals platform

A

proprietary tech focusing on switch control kinase inhibition to target a broad range of kinase mutations and combat cancer mutational resistance

40
Q

what is kryslal biotech

A

commercial stage biopharmaceutical company

41
Q

what is the platform of krystal biotech

A

engineered replication deficient hsv-1

42
Q

what is incyte corporation

A

biopharmaceutical company

43
Q

what is the incyte corporation platform

A

clinical programs of myeloproliferatobe neoplasms, graft versus host diseases, general hematology and oncology, dermatology with a focus on JAK inhibitors

44
Q

what is iteos therapeutics

A

clinical stage biopharmaceutical company

45
Q

what is the platform of iteos

A

highly differenciated immuno oncology treatments

46
Q

what is Syndax Pharmaceuticals?

A

clinical stage biopharma company focusing on small molecule onhibitors and monoclonal antibody treat,ents

47
Q

what is exscientia plc

A

clinical stage biopharmaceutical company developing small molecule drugs with an internal focus on oncology

48
Q

what is the tech od exscientia plc

A

AI-driven drug discovery platform (Centaur Chemist) for quicker target identification, better molecular designs
(efficacy, safety, bioavailability) and more-sensitive biophysical screening techniques of oncogenic factors.

49
Q

what is prime medecine

A

preclinical stage biotech

50
Q

what is the platform of prime medecine

A

gene editing aka prime editing

51
Q

what is 4dmt

A

bio pharma company at clinical stage

52
Q

what is the platform of 4dmt

A

therapeutics vector evolution: make aav vectors for gene delivery of targeted therapied

53
Q

what is uniqure

A

clinical stage and pre clinical company focusing on the development og gene therapoes for rare diseases

54
Q

what os the platform of uniqure

A

-aav based vector delivery system
-gene cassette

55
Q

what is verve therapeutcs

A

clinical stage biopharma for atherosclerotic cardiovascular disease

56
Q

what is verve therapeutocs platform

A

single course in vivo base editing tech combines with novel lipid nanoparticle delivery system

57
Q

what is rocket pharmaceuticals

A

clinical stage biotech company focused on developing first in class gene therapies for cardiovascular and he,atology based henetic diseases

58
Q

what is rocket pharma platform

A

lentiviral virus and adeno associated virus aka aav gene therapies for rare genetic diseases

59
Q

what is kalvista

A

focus on discovery, development and commercialization or oral, small molecule protease inhibitors for diseases with unmet needs

60
Q

what is biocryst

A

Late-stage biotech developing small-molecule and protein therapeutics for complement-mediated and other rare diseases

61
Q

what is biocryst platfprm

A

● Small-molecule and protein therapeutics
● Focus on developing easy to use medications
● Structure-guided drug design using atomic
level predictive modeling and protein
crystalization

62
Q

what is argenx se

A

clinical stage biooharma

63
Q

what is the platform fo argenx se

A

argenx simple antibody platform for discovery/development of therapeutic antibodies with enhanced propertties

64
Q

what is adaptive biotech

A

commercial stage biotech

65
Q

what is adaptibe tech platform

A

cutting edge immune medecine platform
for immune diseasses

66
Q

what is scholar rock

A

clinical stage biotech compa

67
Q

what is scholar rock platform

A

Platform: monoclonal antibody development
● Technology and IP: targets growth factors to modulate their effects in tissues to treat spinal
muscular atrophy, obesity, solid tumors, fibrosis, and anemia.

68
Q

what. isolema pharma

A

Clinical stage biopharmaceutical company using endocrine therapies to create targeted therapies
for women’s cancers with a focus on ER+HER2- metastatic breast cancer

69
Q

what is humacyte

A

clinical stage biotech specializing in the dev and manifacturing of human acellular vesseslswhat

70
Q

what is the platform of humacyte

A

-bioengineered human tissue: absorbable scaffold where tissue creating cells for vesseld formation followed by cell removal for implantation use

71
Q

what is protagonist ther[

A

clinical stahe biopharma

72
Q

what is protagonist therp platform

A

peptide tech platform , they have developped a pipeline of peptide and small molecule compounds that mimic or inhibit therapeuticallt relevant protein and protein interactions

73
Q

what is crispr therapeutocs

A

Biotechnology company that focuses on gene editing using CRISPR Cas9 to treat serious diseases

74
Q

what. isplatform for crispr therapeutcis

A

crispr cas bitch

75
Q

what is blu bird bio

A

A biotechnology company committed to researching, developing, and commercializing potentially curative gene
therapies for severe genetic diseases based on our proprietary lentiviral vector (“LVV”) gene addition platform

76
Q

what is blubird bio platform

A

Proprietary lentiviral vector (“LVV”) gene addition platform; bluebird bio’s investigational gene therapies are
manufactured with a patient’s own hematopoietic – or blood – stem cells. Functional copies of a gene are delivered to a patient’s
stem cells using a delivery system called a “vector.”

77
Q

what is arcturus therapeutic

A

A mRNA medicine and vaccine company that focuses on the discovery, development and
commercialization of vaccine and rare diseases therapeuticsw

78
Q

what is arcturus platform

A

LUNAR® lipid-mediated delivery and STARR™ (Self-amplifying) mRNA Technology

79
Q
A

Business of science (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions