Green book 4 Flashcards
Which of the following is/are true about mumps infection:
a) All patients have bilateral swelling of the parotid glands
b) Asymptomatic infection does not occur
c) It was the commonest cause of viral meningitis in children before 1988
d) Neurological complications can occur without swelling of the salivary glands
e) Mumps is a common cause of sub-fertility
It was the commonest cause of viral meningitis in children before 1988
Neurological complications can occur without swelling of the salivary glands
Mumps vaccine:
a) Is available only in the MMR vaccine
b) A single dose of a mumps antigen containing vaccine is around 64% effective
c) Should not be given if there is a history of mumps
d) Can be given at any age
e) Adverse reactions to the mumps containing vaccines may occur up to 6 weeks’ post
vaccination
Is available only in the MMR vaccine
A single dose of a mumps antigen containing vaccine is around 64% effective
Can be given at any age
Adverse reactions to the mumps containing vaccines may occur up to 6 weeks’ post vaccination
Which of the following is/are true about MMR vaccines:
a) It is effective prophylaxis if given after exposure to mumps infection
b) Will not exacerbate the symptoms if given to someone who is already incubating
mumps infection
c) A mumps like illness occurring 2 days later MMR vaccine is likely to be due to the
vaccine
d) It is better not to offer MMR if there is uncertainty about an individual’s mumps
vaccination status
e) Contact with suspected mumps infection is a good opportunity to offer MMR to a
previously unvaccinated individual
Will not exacerbate the symptoms if given to someone who is already incubating mumps infection
Contact with suspected mumps infection is a good opportunity to offer MMR to a previously unvaccinated individual
The following is/are true about pertussis:
a) The incubation period is between 12 to 20 days
b) Cases are at their most infectious during the early catarrhal phase
c) Cases can be infectious up to 3 weeks after the onset of symptoms
d) In the 2012 Pertussis outbreak the highest incidence of disease was in infants 3 to 6
months of age
e) Pertussis vaccine can also protect against similar illnesses caused by the organism
B. parapertussis
Cases are at their most infectious during the early catarrhal phase
Cases can be infectious up to 3 weeks after the onset of symptoms
Which of the following is/are true about the acellular pertussis vaccines (Infanrix
and Pediacel) used in the UK:
a) They are conjugated vaccines
b) They offer equal or better protection than the whole–cell pertussis vaccine
c) They are only given as part of the combined products (DTaP/IPV/Hib) or DTaP/IPV
or dTaP/IPV)
d) They are thiomersal-free
e) They can be given at the same time as other vaccines such as MMR and Hep B (but
in a different site)
They offer equal or better protection than the whole–cell pertussis vaccine
Are only given as part of the combined products (DTaP/IPV/Hib) or DTaP/IPV or dTaP/IPV)
They are thiomersal-free
Can be given at the same time as other vaccines such as MMR and Hep B (but in a different site)
Which of the following is/are true? For full protection against pertussis, infants
and children under 10 years of age need:
a) Three doses of a pertussis vaccine–containing product with an interval of one month
between each dose and a booster after 3 years
b) Three doses of DTaP/IPV or DTaP/IPV/Hib and a booster if they have never had
pertussis vaccine, but have received 3 doses of vaccine against diphtheria, tetanus
and polio
c) To repeat the course if the primary course is interrupted
d) Full UK schedule should be followed if no reliable history of previous immunisation is
available
e) No further pertussis containing vaccine if they have had a clinical history of
whooping cough
Three doses of a pertussis vaccine–containing product with an interval of one month between each dose and a booster after 3 years
Three doses of DTaP/IPV or DTaP/IPV/Hib and a booster if they have never had pertussis vaccine, but have received 3 doses of vaccine against diphtheria, tetanus and polio
Full UK schedule should be followed if no reliable history of previous immunisation is available
Which of the following is/are true? Pertussis vaccine should not be given to:
a) Those with confirmed anaphylactic reaction to a previous dose of a pertussis-containing
vaccine or to neomycin, streptomycin or polymyxin
b) Pregnant women
c) Premature infants
d) Those with Immunosuppression and HIV infection
e) Those with stable pre-existing neurological condition
Those with confirmed anaphylactic reaction to a previous dose of a pertussis-containing vaccine or to neomycin, streptomycin or polymyxin
Which of the following is/are true about prenatal pertussis vaccination:
a) Vaccination should be offered starting from 26 weeks of gestation
b) Vaccine should be offered in every pregnancy
c) It should not be offered after 32 weeks of pregnancy as it is unlikely to offer any
protection
d) Both Boostrix and Repevax are suitable for use in the prenatal programme
e) In exceptional circumstances Infanrix IPV can be given
Vaccine should be offered in every pregnancy
Both Boostrix and Repevax are suitable for use in the prenatal programme
In exceptional circumstances Infanrix IPV can be given
Which of the following is/are true regarding pneumococcal infection:
a) The majority of infections in adults and children are caused by up to 10 capsular
(sero) types
b) The incubation period is defined as 7-10 days
c) Transmission commonly occurs after transient contact with a case
d) Infections are at their peak in the winter months
e) In general infections are trivial but irritating
The majority of infections in adults and children are caused by up to 10 capsular (sero)types
Infections are at their peak in the winter months
Pneumococcal polysaccharide vaccine:
a) Children under 2 show good antibody responses to this vaccine
b) Covers 23 serotypes
c) Is highly effective at preventing pneumococcal infections, particularly otitis media
d) Is effective at all ages
e) Post immunisation antibodies wane after about 5 years
Covers 23 serotypes
Post immunisation antibodies wane after about 5 years
Pneumococcal conjugate vaccine (PCV):
a) Children require more than one dose to produce effective protection
b) Appears to produce “herd immunity”
c) Contains thiomersal
d) Is available which covers 13 serotypes
e) Is conjugated to a Neisseria meningitidis derived carrier protein
Children require more than one dose to produce effective protection
Appears to produce “herd immunity”
Is available which covers 13 serotypes
Pneumococcal conjugate vaccine (PCV):
a) Was introduced to the UK in 2000
b) Is given to children born on or after 01/01/2020 at 12 weeks and 1 year in the UK
primary vaccination schedule
c) Should be offered routinely as a single dose to anyone over the age of 2 years who
has not completed the primary childhood schedule
d) If the first dose is given very late then a minimum of 4 weeks should be observed
before the booster to ensure appropriate boosting
e) An unimmunised or partially immunised child aged between one and under 2 years
of age should have 2 doses of PCV13 2 months apart
Is given to children born on or after 01/01/2020 at 12 weeks and 1 year in the UK primary vaccination schedule
If the first dose is given very late then a minimum of 4 weeks should be observed before the booster to ensure appropriate boosting
Pneumococcal polysaccharide vaccine:
a) Is recommended for everyone aged 65 years and over
b) Has a primary schedule of 2 doses, given 3 months apart
c) Boosters should be given to all people in clinical risk groups every 5 years
d) Should be given to asplenic children at 1 year
e) Is recommended for all patients with asplenia or splenic dysfunction
Is recommended for everyone aged 65 years and over
Is recommended to all patients with asplenia or splenic dysfunction
Which of the following people should receive pneumococcal vaccines:
a) People with chronic respiratory disease
b) Household contacts of a case of pneumococcal meningitis
c) People who have cerebrospinal fluid leaks
d) Anyone who has developed invasive pneumococcal disease and has not been
vaccinated in the past
e) Any child under 2 years of age with an incomplete vaccine history
People with chronic respiratory disease
People who have cerebrospinal fluid leaks
Anyone who has developed invasive pneumococcal disease and has not been vaccinated in the past
Any child under 2 years of age with an incomplete vaccine history
Which of the following should receive pneumococcal vaccines:
a) At risk children over 2 years should receive a dose of PPV in addition to their primary
PCV doses
b) People with chronic heart disease
c) Diabetics ‘controlled by diet’
d) People with cochlear implants
e) Those at continuous occupational exposure to metal fumes
At risk children over 2 years should receive a dose of PPV in addition to their primary PCV doses
People with chronic heart disease
People with cochlear implants
Those at continuous occupational exposure to metal fumes
Which of the following should not receive pneumococcal vaccines:
a) Pregnant women
b) Premature infants
c) HIV positive people
d) Other people with severe immuno-compromising conditions
e) Breast feeding mothers
There is no correct answer, all the following may receive pneumococcal vaccines
Pneumococcal polysaccharide vaccines:
a) Contain purified capsular polysaccharide
b) Do not prevent exacerbation of chronic bronchitis
c) Can provide limited cross protection against non-vaccine serotypes
d) Provide long-lasting immunity i.e. more than 10 years
e) Contain thiomersal
Contain purified capsular polysaccharide
Do not prevent exacerbation of chronic bronchitis
Which of the following is/are recognised adverse reactions to pneumococcal
vaccines:
a) Most patients who receive PPV23 develop a mild fever
b) Systemic reactions occur quite often with both pneumococcal vaccines
c) Headache is common after PPV23
d) Diarrhoea is common in infants and toddlers following PCV
e) Pain and induration at the vaccine site can last for 3 days following PPV
Pain and induration at the vaccine site can last for 3 days following PPV
Which of the following is/are true:
a) At risk children 12 months to 10 years should also receive one dose of
polysaccharide vaccine after the second birthday
b) Where it is not practical to give pneumococcal vaccine at least 2 weeks before
splenectomy, immunisation should be delayed at least 2 weeks after the operation
c) Children aged between 2 to 10 years who have been fully immunised and then
develop splenic dysfunction should be offered an additional dose of PCV13
d) 13 valent PCV is routinely recommended for all at risk adults
e) Pneumococcal vaccines are contra indicated in pregnant women
At risk children 12 months to 10 years should also receive one dose of polysaccharide vaccine after the second birthday
Where it is not practical to give pneumococcal vaccine at least 2 weeks before splenectomy, immunisation should be delayed at least 2 weeks after the operation
Infection with polioviruses:
a) Is most often asymptomatic
b) Children are more likely to have infection without illness than adults
c) Cases are most infectious just before and up to 6 weeks’ post onset of illness
d) Live vaccine strains may rarely cause paralytic disease
e) The last case of natural polio infection in the UK was in 1954
Is most often asymptomatic
Children are more likely to have infection without illness than adults
Live vaccine strains may rarely cause paralytic disease
Oral polio vaccine (OPV):
a) May protect contacts of vaccinated people
b) Promotes antibody formation in the gut
c) Reduces the frequency of symptomless excretion of wild viruses
d) May cause vaccine associated paralytic polio
e) Is still used for routine vaccination in the UK
May protect contacts of vaccinated people
Promotes antibody formation in the gut
Reduces the frequency of symptomless excretion of wild viruses
May cause vaccine associated paralytic polio