Green book 4 Flashcards

1
Q

Which of the following is/are true about mumps infection:

a) All patients have bilateral swelling of the parotid glands
b) Asymptomatic infection does not occur
c) It was the commonest cause of viral meningitis in children before 1988
d) Neurological complications can occur without swelling of the salivary glands
e) Mumps is a common cause of sub-fertility

A

It was the commonest cause of viral meningitis in children before 1988

Neurological complications can occur without swelling of the salivary glands

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2
Q

Mumps vaccine:
a) Is available only in the MMR vaccine
b) A single dose of a mumps antigen containing vaccine is around 64% effective
c) Should not be given if there is a history of mumps
d) Can be given at any age
e) Adverse reactions to the mumps containing vaccines may occur up to 6 weeks’ post
vaccination

A

Is available only in the MMR vaccine

A single dose of a mumps antigen containing vaccine is around 64% effective

Can be given at any age

Adverse reactions to the mumps containing vaccines may occur up to 6 weeks’ post vaccination

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3
Q

Which of the following is/are true about MMR vaccines:
a) It is effective prophylaxis if given after exposure to mumps infection
b) Will not exacerbate the symptoms if given to someone who is already incubating
mumps infection
c) A mumps like illness occurring 2 days later MMR vaccine is likely to be due to the
vaccine
d) It is better not to offer MMR if there is uncertainty about an individual’s mumps
vaccination status
e) Contact with suspected mumps infection is a good opportunity to offer MMR to a
previously unvaccinated individual

A

Will not exacerbate the symptoms if given to someone who is already incubating mumps infection

Contact with suspected mumps infection is a good opportunity to offer MMR to a previously unvaccinated individual

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4
Q

The following is/are true about pertussis:
a) The incubation period is between 12 to 20 days
b) Cases are at their most infectious during the early catarrhal phase
c) Cases can be infectious up to 3 weeks after the onset of symptoms
d) In the 2012 Pertussis outbreak the highest incidence of disease was in infants 3 to 6
months of age
e) Pertussis vaccine can also protect against similar illnesses caused by the organism
B. parapertussis

A

Cases are at their most infectious during the early catarrhal phase

Cases can be infectious up to 3 weeks after the onset of symptoms

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5
Q

Which of the following is/are true about the acellular pertussis vaccines (Infanrix
and Pediacel) used in the UK:
a) They are conjugated vaccines
b) They offer equal or better protection than the whole–cell pertussis vaccine
c) They are only given as part of the combined products (DTaP/IPV/Hib) or DTaP/IPV
or dTaP/IPV)
d) They are thiomersal-free
e) They can be given at the same time as other vaccines such as MMR and Hep B (but
in a different site)

A

They offer equal or better protection than the whole–cell pertussis vaccine

Are only given as part of the combined products (DTaP/IPV/Hib) or DTaP/IPV or dTaP/IPV)

They are thiomersal-free

Can be given at the same time as other vaccines such as MMR and Hep B (but in a different site)

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6
Q

Which of the following is/are true? For full protection against pertussis, infants
and children under 10 years of age need:
a) Three doses of a pertussis vaccine–containing product with an interval of one month
between each dose and a booster after 3 years
b) Three doses of DTaP/IPV or DTaP/IPV/Hib and a booster if they have never had
pertussis vaccine, but have received 3 doses of vaccine against diphtheria, tetanus
and polio
c) To repeat the course if the primary course is interrupted
d) Full UK schedule should be followed if no reliable history of previous immunisation is
available
e) No further pertussis containing vaccine if they have had a clinical history of
whooping cough

A

Three doses of a pertussis vaccine–containing product with an interval of one month between each dose and a booster after 3 years

Three doses of DTaP/IPV or DTaP/IPV/Hib and a booster if they have never had pertussis vaccine, but have received 3 doses of vaccine against diphtheria, tetanus and polio

Full UK schedule should be followed if no reliable history of previous immunisation is available

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7
Q

Which of the following is/are true? Pertussis vaccine should not be given to:
a) Those with confirmed anaphylactic reaction to a previous dose of a pertussis-containing
vaccine or to neomycin, streptomycin or polymyxin
b) Pregnant women
c) Premature infants
d) Those with Immunosuppression and HIV infection
e) Those with stable pre-existing neurological condition

A

Those with confirmed anaphylactic reaction to a previous dose of a pertussis-containing vaccine or to neomycin, streptomycin or polymyxin

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8
Q

Which of the following is/are true about prenatal pertussis vaccination:
a) Vaccination should be offered starting from 26 weeks of gestation
b) Vaccine should be offered in every pregnancy
c) It should not be offered after 32 weeks of pregnancy as it is unlikely to offer any
protection
d) Both Boostrix and Repevax are suitable for use in the prenatal programme
e) In exceptional circumstances Infanrix IPV can be given

A

Vaccine should be offered in every pregnancy

Both Boostrix and Repevax are suitable for use in the prenatal programme

In exceptional circumstances Infanrix IPV can be given

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9
Q

Which of the following is/are true regarding pneumococcal infection:

a) The majority of infections in adults and children are caused by up to 10 capsular
(sero) types
b) The incubation period is defined as 7-10 days
c) Transmission commonly occurs after transient contact with a case
d) Infections are at their peak in the winter months
e) In general infections are trivial but irritating

A

The majority of infections in adults and children are caused by up to 10 capsular (sero)types

Infections are at their peak in the winter months

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10
Q

Pneumococcal polysaccharide vaccine:

a) Children under 2 show good antibody responses to this vaccine
b) Covers 23 serotypes
c) Is highly effective at preventing pneumococcal infections, particularly otitis media
d) Is effective at all ages
e) Post immunisation antibodies wane after about 5 years

A

Covers 23 serotypes

Post immunisation antibodies wane after about 5 years

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11
Q

Pneumococcal conjugate vaccine (PCV):

a) Children require more than one dose to produce effective protection
b) Appears to produce “herd immunity”
c) Contains thiomersal
d) Is available which covers 13 serotypes
e) Is conjugated to a Neisseria meningitidis derived carrier protein

A

Children require more than one dose to produce effective protection

Appears to produce “herd immunity”

Is available which covers 13 serotypes

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12
Q

Pneumococcal conjugate vaccine (PCV):
a) Was introduced to the UK in 2000
b) Is given to children born on or after 01/01/2020 at 12 weeks and 1 year in the UK
primary vaccination schedule
c) Should be offered routinely as a single dose to anyone over the age of 2 years who
has not completed the primary childhood schedule
d) If the first dose is given very late then a minimum of 4 weeks should be observed
before the booster to ensure appropriate boosting
e) An unimmunised or partially immunised child aged between one and under 2 years
of age should have 2 doses of PCV13 2 months apart

A

Is given to children born on or after 01/01/2020 at 12 weeks and 1 year in the UK primary vaccination schedule

If the first dose is given very late then a minimum of 4 weeks should be observed before the booster to ensure appropriate boosting

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13
Q

Pneumococcal polysaccharide vaccine:

a) Is recommended for everyone aged 65 years and over
b) Has a primary schedule of 2 doses, given 3 months apart
c) Boosters should be given to all people in clinical risk groups every 5 years
d) Should be given to asplenic children at 1 year
e) Is recommended for all patients with asplenia or splenic dysfunction

A

Is recommended for everyone aged 65 years and over

Is recommended to all patients with asplenia or splenic dysfunction

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14
Q

Which of the following people should receive pneumococcal vaccines:
a) People with chronic respiratory disease
b) Household contacts of a case of pneumococcal meningitis
c) People who have cerebrospinal fluid leaks
d) Anyone who has developed invasive pneumococcal disease and has not been
vaccinated in the past
e) Any child under 2 years of age with an incomplete vaccine history

A

People with chronic respiratory disease

People who have cerebrospinal fluid leaks

Anyone who has developed invasive pneumococcal disease and has not been vaccinated in the past

Any child under 2 years of age with an incomplete vaccine history

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15
Q

Which of the following should receive pneumococcal vaccines:
a) At risk children over 2 years should receive a dose of PPV in addition to their primary
PCV doses
b) People with chronic heart disease
c) Diabetics ‘controlled by diet’
d) People with cochlear implants
e) Those at continuous occupational exposure to metal fumes

A

At risk children over 2 years should receive a dose of PPV in addition to their primary PCV doses

People with chronic heart disease

People with cochlear implants

Those at continuous occupational exposure to metal fumes

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16
Q

Which of the following should not receive pneumococcal vaccines:

a) Pregnant women
b) Premature infants
c) HIV positive people
d) Other people with severe immuno-compromising conditions
e) Breast feeding mothers

A

There is no correct answer, all the following may receive pneumococcal vaccines

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17
Q

Pneumococcal polysaccharide vaccines:

a) Contain purified capsular polysaccharide
b) Do not prevent exacerbation of chronic bronchitis
c) Can provide limited cross protection against non-vaccine serotypes
d) Provide long-lasting immunity i.e. more than 10 years
e) Contain thiomersal

A

Contain purified capsular polysaccharide

Do not prevent exacerbation of chronic bronchitis

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18
Q

Which of the following is/are recognised adverse reactions to pneumococcal
vaccines:
a) Most patients who receive PPV23 develop a mild fever
b) Systemic reactions occur quite often with both pneumococcal vaccines
c) Headache is common after PPV23
d) Diarrhoea is common in infants and toddlers following PCV
e) Pain and induration at the vaccine site can last for 3 days following PPV

A

Pain and induration at the vaccine site can last for 3 days following PPV

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19
Q

Which of the following is/are true:
a) At risk children 12 months to 10 years should also receive one dose of
polysaccharide vaccine after the second birthday
b) Where it is not practical to give pneumococcal vaccine at least 2 weeks before
splenectomy, immunisation should be delayed at least 2 weeks after the operation
c) Children aged between 2 to 10 years who have been fully immunised and then
develop splenic dysfunction should be offered an additional dose of PCV13
d) 13 valent PCV is routinely recommended for all at risk adults
e) Pneumococcal vaccines are contra indicated in pregnant women

A

At risk children 12 months to 10 years should also receive one dose of polysaccharide vaccine after the second birthday

Where it is not practical to give pneumococcal vaccine at least 2 weeks before splenectomy, immunisation should be delayed at least 2 weeks after the operation

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20
Q

Infection with polioviruses:

a) Is most often asymptomatic
b) Children are more likely to have infection without illness than adults
c) Cases are most infectious just before and up to 6 weeks’ post onset of illness
d) Live vaccine strains may rarely cause paralytic disease
e) The last case of natural polio infection in the UK was in 1954

A

Is most often asymptomatic

Children are more likely to have infection without illness than adults

Live vaccine strains may rarely cause paralytic disease

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21
Q

Oral polio vaccine (OPV):

a) May protect contacts of vaccinated people
b) Promotes antibody formation in the gut
c) Reduces the frequency of symptomless excretion of wild viruses
d) May cause vaccine associated paralytic polio
e) Is still used for routine vaccination in the UK

A

May protect contacts of vaccinated people

Promotes antibody formation in the gut

Reduces the frequency of symptomless excretion of wild viruses

May cause vaccine associated paralytic polio

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22
Q

Inactivated polio vaccine (IPV):

a) Is made from 2 polio virus strains
b) Is available in both intramuscular and oral preparations
c) Should not be used if a vaccination course was started with OPV
d) Is recommended as Td/IPV for those over 10 years
e) Is recommended for some laboratory workers

A

Is recommended as Td/IPV for those over 10 years

Is recommended for some laboratory workers

23
Q

A 21-year-old attends your surgery for travel vaccines. He is backpacking around
the world, his itinerary uncertain but includes India, Thailand, Australia and South
America. He has had a primary course of diphtheria, tetanus and polio vaccines,
but missed his preschool and school leaving booster vaccinations.

So far as protection against polio is concerned:

a) He already has sufficient protection
b) He needs just one dose of Td/IPV to continue his course
c) As he had tetanus vaccine less than 10 years ago the risk of a local reaction means
it is unwise to give him Td/IPV
d) He should be given a dose of Td/IPV, and a further dose of Td/IPV in 10 years’ time
e) He should be given OPV as he may be visiting countries where polio is still a
problem

A

He needs just one dose of Td/IPV to continue his course, (but a further dose of Td/IPV in 10 years’ time to complete his course)

He should be given a dose of Td/IPV, and a further dose of Td/IPV in 10 years’ time

24
Q

Which of the following statements is/are true about rabies vaccines:
a) There are currently 2 rabies vaccines licensed for use in the UK
b) The vaccines available in the UK are thiomersal free
c) The vaccines are inactivated, do not contain live organisms and cannot cause the
disease against which they protect
d) The vaccines should not be used interchangeably to provide protection both pre- or
post-exposure
e) They can be stored frozen

A

There are currently 2 rabies vaccines licensed for use in the UK

The vaccines available in the UK are thiomersal free

The vaccines are inactivated, do not contain live organisms and cannot cause the disease against which they protect

25
Q

Which of the following is/are true? Pre-exposure (prophylactic) immunisation with
rabies vaccine should be offered in the UK to:
a) Laboratory workers handling the virus
b) Those working in DEFRA authorised quarantine premises
c) Those who regularly handle bats
d) Those living in or travelling for more than one month to rabies-enzootic areas
e) Anyone travelling abroad with a dog

A

Laboratory workers handling the virus

Those working in DEFRA authorised quarantine premises

Those who regularly handle bats

Those living in or travelling for more than one month to rabies-enzootic areas

26
Q

Which of the following is/are true about rabies vaccine:
a) Pre-exposure rabies vaccine should not be given to those who have had a confirmed
anaphylactic reaction to a previous dose of rabies vaccine
b) Post exposure vaccine should be given via the intradermal route
c) Pregnant and breast-feeding mothers should only receive pre-exposure rabies
vaccine if the risk of exposure is high and rapid access to post-exposure prophylaxis
is limited
d) There are no absolute contraindications to post-exposure rabies vaccine
e) The vaccine should be given to immunosuppressed and HIV patients regardless of
their CD4 count

A

Pre-exposure rabies vaccine should not be given to those who have had a confirmed anaphylactic reaction to a previous dose of rabies vaccine

Pregnant and breast-feeding mothers should only receive pre-exposure rabies vaccine if the risk of exposure is high and rapid access to post-exposure prophylaxis is limited

There are no absolute contraindications to post-exposure rabies vaccine

The vaccine should be given to immunosuppressed and HIV patients regardless of their CD4 count

27
Q

An immunocompetent previously unimmunised individual at high-risk of rabies
(composite rabies risk red) who sustained an exposure yesterday requires the
following as post-exposure prophylaxis:
a) Two doses of rabies vaccine on days 0 and 3
b) Four doses of rabies vaccines on days 0, 3, 7 and 14
c) Five doses of rabies vaccine on days 0, 3 7, 14 and 30
d) Four doses of rabies vaccine on days 0, 3, 7 and 21, plus Hyper-Immune Rabies
Immunoglobulin (HRIG) on day 0
e) Two doses of rabies vaccine on days 0 and 3, plus HRIG on day 0

A

Four doses of rabies vaccine on days 0, 3, 7 and 21, plus Hyper-Immune Rabies Immunoglobulin (HRIG) on day 0

28
Q

Respiratory Syncytial Virus (RSV):
a) Causes bronchiolitis in infants
b) Has an incubation period varying from 5 to 10 days
c) Has neuraminidase and haemagglutin surface glycoproteins in common with
influenza virus
d) May infect individuals repeatedly with the same strain
e) The disease severity is influenced by the virus subtype

A

Causes bronchiolitis in infants

May infect individuals repeatedly with the same strain

29
Q

Infections with RSV:

a) Result in hospitalisation of 10% of infected children
b) Commonly peak in the spring in the UK
c) May cause ear infections
d) May increase risk of developing asthma later in childhood
e) Will have occurred in almost all children at least once by the age of 2 years

A

May cause ear infections

May increase risk of developing asthma later in childhood

Will have occurred in almost all children at least once by the age of 2 years

30
Q

Palivizumab:

a) Is a conjugated vaccine
b) Targets the F protein of RSV
c) Provides passive immunisation
d) Requires weekly administration during the RSV season
e) Is indicated for high risk adults as well as children

A

Targets the F protein of RSV

Provides passive immunisation

31
Q

Palivizumab:
a) Is given by IM injection
b) Should not be given at the same time as vaccines administered as part of the
childhood immunisation programme
c) Should preferably be given in the deltoid region
d) Has a recommended dose of 15 mg/kg of body weight given once a month
e) During the RSV season, up to a maximum of 10 doses should be given

A

Is given by IM injection

Has a recommended dose of 15 mg/kg of body weight given once a month

32
Q

During the RSV season Palivizumab should be considered for the following:
a) Children born at 35 weeks or less and under 1 year of age at the onset of the RSV
season
b) Children under 2 years of age with haemodynamically significant congenital heart
disease
c) Children under the age of 2 years with asthma who are frequently hospitalised
d) Adults undergoing cardiac surgery at the beginning of the RSV season
e) Children under 2 years of age requiring treatment for bronchopulmonary dysplasia in
the previous 6 months

A

Children under 2 years of age with haemodynamically significant congenital heart disease

Children under 2 years of age requiring treatment for bronchopulmonary dysplasia in the previous 6 months

33
Q

Children with the following underlying history should be considered for treatment
with Palivizumab:
a) Asplenia
b) Severe combined immunodefiency syndrome (SCID)
c) Requiring long term ventilation
d) Acyanotic chronic heart disease
e) HIV infection

A

Severe combined immunodeficiency syndrome (SCID)

Requiring long term ventilation

Acyanotic chronic heart disease

34
Q

The following is/are true about rotavirus vaccines:
a) The 2 licensed rotavirus vaccines Rotarix® and RotaTeq® are not interchangeable
b) The vaccine is 95% effective at protecting against rotavirus infection in the first 2
years of life
c) It is an inactivated vaccine
d) The vaccine is not injectable
e) The vaccine may be frozen before use

A

The 2 licensed rotavirus vaccines Rotarix® and RotaTeq® are not interchangeable

The vaccine is not injectable

35
Q

The ideal recommended schedule for Rotarix® is:

a) One dose at the 4-month vaccination visit
b) 2 doses at the 2 and 3-month vaccination visits
c) 2 doses at the 3 and 4-month vaccination visits
d) 2 doses at 15 weeks and 24 weeks
e) One dose given any time before 16 weeks

A

2 doses at the 2 and 3-month vaccination visits

36
Q

In line with WHO recommendations infants who have not yet received a first dose
of rotavirus vaccine should not be commenced on Rotarix® if they are older than:
a) 10 weeks
b) 12 weeks
c) 24 weeks
d) 20 weeks
e) 15 weeks

A

15 weeks

37
Q

Rotarix® is contraindicated in:

a) Infants under 12 weeks of age
b) Infants with SCID
c) Infants with fructose intolerance
d) Premature infants
e) Infants who are HIV positive

A

Infants with SCID

Infants with fructose intolerance

38
Q

Which of the following is/are true:
a) There should be an interval of a month between a dose of rotavirus vaccine and
BCG
b) Rotavirus and BCG can be given at any time before or after each other
c) If the infant spits out the vaccine up to 2 replacement doses may be given at the
same vaccination visit
d) The vaccine needs to be reconstituted from powder before administration
e) Rotarix® vaccine is supplied as an oral suspension of a cloudy fluid

A

Rotavirus and BCG can be given at any time before or after each other

39
Q

In relation to intussusception:

a) The background risk of intussusception peaks in the UK at 12 months of age
b) Intussusception mainly occurs after surgery to the intestine
c) The annual incidence in the UK is 120 cases per 100,000 children
d) Rotarix® should not be given to infants with a previous history of intussusception
e) Rotarix® may be associated with a small risk of intussusception

A

The annual incidence in the UK is 120 cases per 100,000 children

Rotarix® should not be given to infants with a previous history of intussusception

Rotarix® may be associated with a small risk of intussusception

40
Q

Which of the following is/are true about Rubella:
a) It is caused by a herpes virus
b) The incubation period is 10-12 days
c) Clinical diagnosis is usually reliable
d) The infectious period is from one week before symptoms to 4 days after the onset of
rash
e) The rash is generally vesicular

A

The infectious period is from one week before symptoms to 4 days after the onset of rash

41
Q

Recognised complications of Rubella include:

a) Arthralgia
b) Parotid swelling
c) Thrombocytopaenia
d) Ulcerative colitis
e) Post–infectious encephalitis

A

Arthralgia

Thrombocytopaenia

Post–infectious encephalitis

42
Q

Which of the following is/are true about Congenital Rubella Syndrome (CRS):
a) Infection in the first 8-10 weeks of pregnancy results in damage in 10% of surviving
infants
b) Fetal damage is rare following infection after 16 weeks of pregnancy
c) Is always apparent at birth
d) Has been documented in babies born to women who have inadvertently given MMR
vaccine in pregnancy
e) To prevent the risk of CRS in a subsequent pregnancy, women who are found to be
non-immune in pregnancy should receive MMR vaccine after delivery

A

Fetal damage is rare following infection after 16 weeks of pregnancy

To prevent the risk of CRS in a subsequent pregnancy women who are found to be non-immune in pregnancy should receive MMR vaccine after delivery

43
Q

Which of the following is/are true about MMR vaccine and Rubella:
a) Children should not receive MMR vaccine if their mothers are in early pregnancy
b) A mild rubella like rash may be seen 2-3 weeks after a dose of MMR vaccine
c) Arthralgia, probably due to the rubella component, is a reported rare occurrence
after MMR.
d) ITP following MMR is more likely to be due to measles than the rubella component
e) Small amounts of rubella vaccine virus have been found in breast milk, but this is not
harmful to the baby nor a contra-indication to MMR immunisation whilst breastfeeding

A

A mild rubella like rash may be seen 2-3 weeks after a dose of MMR vaccine

Arthralgia, probably due to the rubella component, is a reported rare occurrence after MMR

Small amounts of rubella vaccine virus have been found in breast milk, but this is not harmful to the baby nor a contra-indication to MMR immunisation whilst breast-feeding

44
Q

Which of the following is/are true about MMR vaccine and Rubella:
a) MMR vaccine may occasionally provide effective post exposure prophylaxis
following contact with rubella
b) MMR vaccine should not be given if there is any likelihood a person is already
incubating rubella
c) Termination of pregnancy should not be recommended following inadvertent
administration of MMR to a pregnant woman
d) Where rubella non-immune women have received anti-D immunoglobulin post
partum the dose of MMR vaccine should be deferred.
e) A blood transfusion around the time of delivery may affect the response to MMR
vaccine given post partum

A

Termination of pregnancy should not be recommended following inadvertent administration of MMR to a pregnant woman

A blood transfusion around the time of delivery may affect the response to MMR vaccine given post-partum

45
Q

Which of the following is/are true:
a) The selective vaccination policy of offering single dose rubella vaccination to
teenage girls in the UK ceased in 1999
b) A single dose of rubella – containing vaccine confers around 85-90% protection
against rubella
c) Satisfactory evidence of rubella protection includes documentation of a positive
antibody result for rubella or having received one dose of rubella containing vaccine
or MMR.
d) Human normal immunoglobulin (HNIG) is not recommended for post-exposure
protection against rubella
e) The diagnosis of rubella con be confirmed non-invasively by testing for specific IgM
in oral fluid (saliva)

A

Human normal immunoglobulin (HNIG) is not recommended for post-exposure protection against rubella

The diagnosis of rubella con be confirmed non-invasively by testing for specific IgM in oral fluid (saliva)

46
Q

The following is/are true about shingles:
a) The estimated lifetime risk of acquiring shingles is about one in 4
b) It can be acquired from another individual who has chicken pox
c) The rash typically lasts between 2 to 4 weeks
d) Ophthalmic zoster occurs in about 4% of cases
e) Individuals with active lesions can transmit VZV to susceptible individuals to cause
chicken pox

A

The estimated lifetime risk of acquiring shingles is about one in 4

The rash typically lasts between 2 and 4 weeks

Individuals with active lesions can transmit VZV to susceptible individuals to cause chicken pox

47
Q

The following is/are true:
a) The accepted definition of Post Herpetic Neuralgia (PHN) is pain that persists for 60
days after the onset of rash
b) The risk of Post Herpetic Neuralgia (PHN) decreases after the age of 79
c) Giving Zostavax to a person with symptoms of Post Herpetic Neuralgia (PHN) may
offer some therapeutic benefit
d) “Herpes zoster ophthalmicus” may result in glaucoma
e) Most deaths linked to dissemination of reactivated varicella virus are attributable to
encephalitis

A

“Herpes zoster ophthalmicus” may result in glaucoma

48
Q

The following is/are true about Zostavax:
a) It contains a strain of varicella zoster virus at significantly higher dose than the
Varivax varicella vaccine
b) It reduces the incidence of shingles in those aged 60 and 70 by over 70%
c) It can be administered simultaneously with oral antiviral agents
d) It can be administered at the same time as inactivated influenza vaccine
e) It should not be administered at the same time as 23 valent pneumococcal vaccine
as it gives an inferior VZV antibody response

A

It contains a strain of varicella zoster virus at significantly higher dose than the Varivax varicella vaccine

It can be administered at the same time as inactivated influenza vaccine

49
Q

The course of Zostavax consists of:

a) A single dose
b) 2 doses one month apart
c) 3 doses one month apart
d) A single dose with a booster dose one year later
e) A single dose with a booster dose 3 years later

A

A single dose

50
Q

The administration route for Zostavax is:

a) Intradermal
b) Subcutaneous
c) Intramuscular
d) Intravascular
e) Intranasal

A

Subcutaneous

51
Q

Zostavax should not be administered to:

a) Patients with a previous history of shingles over a year ago
b) Patients without a previous history of chicken pox
c) Patients with symptoms of Post Herpetic Neuralgia (PHN)
d) Patients using topical acyclovir
e) Patients with symptoms of shingles

A

Patients with symptoms of Post Herpetic Neuralgia (PHN)

Patients with symptoms of shingles

52
Q

Reported adverse reactions to Zostavax include:

a) Headache
b) Pruritis
c) Fever
d) Idiopathic Thrombocytopaenic purpura (ITP)
e) Myalgia

A

Headache

Pruritis

53
Q

Contraindications to receiving Zostavax include:

a) Lymphoma
b) Parkinson’s Disease
c) Macular degeneration
d) Inhaled corticosteroids
e) Previous anaphylactic reaction to gelatin

A

Lymphoma

Previous anaphylactic reaction to gelatin

54
Q

Which of the following is/are true regarding smallpox and smallpox vaccination:
a) The world was declared smallpox free in December 1979
b) Members of smallpox response teams should be vaccinated against smallpox
c) Staff working in laboratories with monkey pox should be considered for vaccination
against smallpox
d) People opening crypts where smallpox cases may have been buried should be
vaccinated against smallpox
e) Smallpox vaccine can be given safely to anyone

A

The world was declared smallpox free in December 1979

Members of smallpox response teams should be considered for vaccination against smallpox

Staff working in laboratories with monkey pox should be considered for vaccination against smallpox