Grave's Disease Flashcards
1
Q
def of Grave’s Disease
A
also known as toxic diffuse goiter
an autoimmune disease that affects the thyroid
it is the most common cause of hyperthyroidism
2
Q
aetiology/risk factors of GD
A
stimulation of the thyroid by TSH receptor antibodies which causes thyroid hormone overproduction
genetic role
being female is a rf
moderate alcohol consumption DECREASES risk of GD
smoking is a rf
3
Q
history of GD
A
heat intolerance sweating weight loss diarrhoea tremor
4
Q
examination of GD
A
tachycardia
diffuse goitre
exopthalmos
pretibial myoxoedema
5
Q
epi of GD
A
most common cause of hyperthyroidism
common in 40-60yrs
6
Q
investigations performed in suspected GD
A
suppressed TSH (nr 0.4-4.0)
elevated serum free T4
elevated serum free or total T3
elevated T3RU, free T3 index
